U.S. Route 45 (US 45) is a major north-south United States highway and a border-to-border route, from Lake Superior to the Gulf of Mexico. A sign at the...

U.S. Route 45 (US 45) in the state of Illinois is a major north–south U.S. Highway that runs from the Brookport Bridge over the Ohio River at Brookport...

U.S. Highway 45 (US 45) runs north–south through the eastern and northern portions of the state of Wisconsin. Also called Highway 45, it runs from the...

U.S. Route 45 Alternate (US 45 Alternate, also signed as US 45A) is a 62.9-mile-long (101.2 km) alternate route of US 45 in northeastern Mississippi, running...

1970s moved the routing of US 45 near Rockland before it was reversed soon afterwards. A segment of roadway that formerly carried US 45 is the site of...

In the U.S. state of Alabama, U.S. Route 45 (US 45) is a 60-mile-long (97 km) north–south United States Highway in the east south central state of Alabama...

U.S. Route 45 (US 45) enters Kentucky at Fulton in Fulton County and travels northeast through Hickman County, Graves County, and McCracken County. After...

U.S. Route 45 (US 45) in Tennessee extends from the Mississippi state line to the Kentucky state line in West Tennessee, passing through the cities of...

U.S. Route 54 (US 54) is an east–west United States Highway that runs northeast–southwest for 1,197 miles (1,926 km) from El Paso, Texas, to Griggsville...

U.S. Route 75 is a north–south U.S. Highway that runs 1,239 miles (1,994 km) in the central United States. The highway's northern terminus is located at...