• Thumbnail for Ubiquitin
    Ubiquitin is a small (8.6 kDa) regulatory protein found in most tissues of eukaryotic organisms, i.e., it is found ubiquitously. It was discovered in...
    98 KB (11,068 words) - 18:25, 16 July 2024
  • Thumbnail for Ubiquitin ligase
    A ubiquitin ligase (also called an E3 ubiquitin ligase) is a protein that recruits an E2 ubiquitin-conjugating enzyme that has been loaded with ubiquitin...
    24 KB (2,754 words) - 03:25, 27 May 2024
  • Thumbnail for Proteasome
    protein called ubiquitin. The tagging reaction is catalyzed by enzymes called ubiquitin ligases. Once a protein is tagged with a single ubiquitin molecule,...
    105 KB (12,671 words) - 14:50, 6 June 2024
  • Thumbnail for SUMO enzymes
    transfer of SUMO protein to other proteins). The Small Ubiquitin-related Modifier, SUMO-1, is a ubiquitin-like family member that is conjugated to its substrates...
    5 KB (707 words) - 02:58, 9 November 2021
  • Thumbnail for DTX3L
    Deltex E3 ubiquitin ligase 3L is a protein that in humans is encoded by the DTX3L gene. It functions as an ubiquitin ligase (E3), and is over-expressed...
    8 KB (1,057 words) - 02:55, 21 July 2024
  • Thumbnail for Ubiquitin C
    encoded by the UBC gene in humans. Polyubiquitin-C is one of the sources of ubiquitin, along with UBB, UBA52, and RPS27A. UBC gene is one of the two stress-regulated...
    37 KB (4,261 words) - 21:30, 23 December 2023
  • Thumbnail for Ubiquitin B
    Ubiquitin is a protein that in humans is encoded by the UBB gene. Ubiquitin is one of the most conserved proteins known in eukaryotic organisms. Ubiquitin...
    8 KB (996 words) - 21:12, 21 June 2024
  • Thumbnail for Ubiquitin-binding domain
    Ubiquitin-binding domains (UBDs) are protein domains that recognise and bind non-covalently to ubiquitin through protein-protein interactions. As of 2019...
    6 KB (658 words) - 17:44, 22 June 2022
  • Linear ubiquitin chain assembly complex (LUBAC) is a multi-protein complex and the only known E3 ubiquitin ligase able to conjugate ubiquitin in a head-to-tail...
    12 KB (1,247 words) - 08:33, 18 August 2023
  • Thumbnail for Ubiquitin-interacting motif
    In molecular biology, the Ubiquitin-Interacting Motif (UIM), or 'LALAL-motif', is a sequence motif of about 20 amino acid residues, which was first described...
    6 KB (604 words) - 06:36, 26 April 2024