• Thumbnail for DNA repair protein XRCC4
    protein XRCC4 (hXRCC4) also known as X-ray repair cross-complementing protein 4 is a protein that in humans is encoded by the XRCC4 gene. XRCC4 is also...
    43 KB (5,681 words) - 00:50, 14 June 2024
  • Thumbnail for Non-homologous end-joining factor 1
    Non-homologous end-joining factor 1 (NHEJ1), also known as Cernunnos or XRCC4-like factor (XLF), is a protein that in humans is encoded by the NHEJ1 gene...
    13 KB (1,652 words) - 12:24, 7 November 2023
  • cross-complementing protein 4 (XRCC4), DNA ligase IV, non-homologous end-joining factor 1 (NHEJ1; also known as Cernunnos or XRCC4-like factor [XLF]), the recently...
    21 KB (2,860 words) - 07:32, 14 March 2024
  • Thumbnail for DNA ligase 4
    It is also essential for V(D)J recombination. Lig4 forms a complex with XRCC4, and further interacts with the DNA-dependent protein kinase (DNA-PK) and...
    15 KB (1,821 words) - 05:44, 11 June 2024
  • Thumbnail for Non-homologous end joining
    complex, consisting of the catalytic subunit DNA ligase IV and its cofactor XRCC4 (Dnl4 and Lif1 in yeast), performs the ligation step of repair. XLF, also...
    28 KB (3,679 words) - 19:28, 3 December 2023
  • Thumbnail for Motor neuron diseases
    double-strand breaks where it acts as a scaffold for the recruitment of the XRCC4-DNA ligase protein complex that then acts to repair double-strand breaks...
    21 KB (2,137 words) - 22:21, 9 July 2024
  • Thumbnail for DNA ligase
    been found to be present in mitochondria. DNA ligase 4: complexes with XRCC4. It catalyzes the final step in the non-homologous end joining DNA double-strand...
    23 KB (2,787 words) - 00:53, 18 June 2024
  • Thumbnail for Double-strand break repair model
    subunit (DNA-PKcs), DNA Ligase IV and X-ray cross complementing protein 4 (XRCC4) to form a bridge and bring both ends of the damaged DNA strands together...
    34 KB (4,127 words) - 00:57, 25 July 2024
  • Thumbnail for Werner syndrome
    WRN protein also physically interacts with the major NHEJ factor X4L4 (XRCC4-DNA ligase 4 complex). X4L4 stimulates WRN exonuclease activity that likely...
    36 KB (4,516 words) - 11:08, 15 July 2024
  • XLF may refer to: XLF (protein), XRCC4-like factor .xlf, the filename extension for XLIFF ICAO code for XL Airways France This disambiguation page lists...
    167 bytes (52 words) - 20:02, 4 December 2019