• Thumbnail for NF-κB
    B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription of DNA, cytokine production and cell survival. NF-κB...
    89 KB (9,817 words) - 08:00, 10 June 2024
  • lymphocytes. The IκB kinase enzyme complex is part of the upstream NF-κB signal transduction cascade. The IκBα (inhibitor of nuclear factor kappa B) protein inactivates...
    14 KB (1,447 words) - 09:31, 22 December 2023
  • Thumbnail for T-cell receptor
    degradation of I-κB. I-κB blocks the NLS of NF-κB therefore preventing its translocation to the nucleus. Once I-κB is degraded, it cannot bind to NF-κB and the...
    43 KB (5,370 words) - 03:09, 26 June 2024
  • Thumbnail for CHUK
    by the CHUK gene. IKK-α is part of the IκB kinase complex that plays an important role in regulating the NF-κB transcription factor. However, IKK-α has...
    23 KB (2,765 words) - 20:13, 7 July 2024
  • Thumbnail for Tumor necrosis factor
    normally binds to NF-κB and inhibits its translocation, is phosphorylated by IKK and subsequently degraded, releasing NF-κB. NF-κB is a heterodimeric...
    52 KB (6,311 words) - 06:02, 26 July 2024
  • Look up NF or nf in Wiktionary, the free dictionary. NF may refer to: NF (rapper), American hip hop musician NF (EP), 2014 Neurofibromatosis, a medical...
    2 KB (269 words) - 16:56, 24 January 2024
  • Thumbnail for B-cell receptor
    protein that cleaves A20, an inhibitory protein of NF-κB signaling (which acts by deubiquitylating NF-κB's ubiquitylation substrates, having an inhibitory...
    18 KB (2,173 words) - 16:05, 30 November 2023
  • Thumbnail for RELA
    a REL-associated protein involved in NF-κB heterodimer formation, nuclear translocation and activation. NF-κB is an essential transcription factor complex...
    56 KB (6,507 words) - 07:54, 19 July 2024
  • Thumbnail for Withaferin A
    derivatives are synthesized by regio/stereoselective Michael addition to ring A. NF-κB is a transcription factor that regulates many genes involved in cell survival...
    9 KB (764 words) - 13:54, 5 March 2024
  • Thumbnail for Diffuse large B-cell lymphoma
    exhibit pathologically overactive NF-κB, PI3K/AKT/mTOR, JAK-STAT0, MAPK/ERK, B-cell receptor, toll-like receptor, and NF-κB signaling pathways and thereby...
    69 KB (8,143 words) - 18:36, 22 January 2024