Proteostasis is the dynamic regulation of a balanced, functional proteome. The proteostasis network includes competing and integrated biological pathways...
25 KB (2,922 words) - 16:16, 10 January 2024
Hallmarks of aging (section Loss of proteostasis)
Telomere shortening (or telomere attrition) Epigenetic alterations Loss of proteostasis Antagonistic hallmarks (responses to damage) Deregulated nutrient sensing...
40 KB (4,313 words) - 04:16, 4 May 2024
temperatures, oxidative stress, and heavy metals. In a normal cell, proteostasis (protein homeostasis) must be maintained because proteins are the main...
21 KB (2,437 words) - 05:40, 27 May 2024
methylation patterns, from hypomethylation to hypermethylation. loss of proteostasis (protein folding and proteolysis) deregulated nutrient sensing (relating...
90 KB (10,704 words) - 22:31, 4 July 2024
Retrieved 2022-04-20. "Professor Richard Morimoto - Proteostasis Symposium 2017". Proteostasis Symposium 2017. Retrieved 2018-08-01. "Professor Richard...
41 KB (4,168 words) - 05:41, 24 April 2024
and identified lineage-specific variants affecting DNA repair genes, proteostasis, metabolism regulation and immune response as key processes during the...
19 KB (1,674 words) - 08:29, 13 July 2024
Ubiquitin is implicated in neurodegenerative diseases associated with proteostasis dysfunction, including Alzheimer's disease, motor neuron disease, Huntington's...
98 KB (11,068 words) - 18:25, 16 July 2024
metabolism Mitochondrial diseases Phosphorus metabolism disorders Porphyrias Proteostasis deficiencies Metabolic skin diseases Wasting syndrome Water-electrolyte...
10 KB (778 words) - 18:19, 16 May 2024
Multiprotein complex used in cellular proteostasis...
6 KB (433 words) - 01:25, 14 June 2024
Cellular, and Developmental Biology in 1995. Crews studies controlled proteostasis, i.e., the pharmacological modulation of protein turnover. In 2001, Crews...
31 KB (2,873 words) - 05:59, 14 July 2024