• Thumbnail for Proteasome
    Proteasomes are protein complexes which degrade ubiquitin-tagged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Enzymes that...
    105 KB (12,670 words) - 08:02, 23 August 2024
  • Thumbnail for Proteasome inhibitor
    Proteasome inhibitors (INN stem –zomib) are drugs that block the action of proteasomes, cellular complexes that break down proteins. They are being studied...
    9 KB (1,094 words) - 16:23, 3 December 2023
  • Thumbnail for Ubiquitin
    affects proteins in many ways: it can mark them for degradation via the proteasome, alter their cellular location, affect their activity, and promote or...
    97 KB (11,021 words) - 17:45, 18 September 2024
  • In enzymology, a proteasome ATPase (EC 3.6.4.8) is an enzyme that catalyzes the chemical reaction ATP + H2O ⇌ {\displaystyle \rightleftharpoons } ADP +...
    2 KB (143 words) - 13:26, 27 August 2023
  • Proteasome accessory factor E (abbreviated PafE, also known as bacterial proteasome activator or Bpa) is an ATP-independent proteasome activator of Mycobacterium...
    7 KB (760 words) - 13:24, 23 August 2022
  • Thumbnail for Proteasome endopeptidase complex
    prosome, multicatalytic proteinase (complex), MCP, proteasome, large multicatalytic protease, proteasome organelle, alkaline protease, 26S protease, tricorn...
    2 KB (255 words) - 15:34, 26 August 2023
  • Thumbnail for PSMB5
    Proteasome subunit beta type-5 also known as 20S proteasome subunit beta-5 is a protein that in humans is encoded by the PSMB5 gene. This protein is one...
    25 KB (3,119 words) - 07:57, 23 August 2024
  • Thumbnail for PSMB1
    Proteasome subunit beta type-1 also known as 20S proteasome subunit beta-6 (based on systematic nomenclature) is a protein that in humans is encoded by...
    25 KB (3,183 words) - 04:46, 19 October 2022
  • Thumbnail for MHC class I
    peptides generated mainly from the degradation of cytosolic proteins by the proteasome. The MHC I: peptide complex is then inserted via the endoplasmic reticulum...
    21 KB (2,610 words) - 08:24, 9 August 2024
  • Thumbnail for PSMB4
    Proteasome subunit beta type-4 also known as 20S proteasome subunit beta-7 (based on systematic nomenclature) is a protein that in humans is encoded by...
    24 KB (3,031 words) - 08:14, 3 December 2023