Romiplostim, sold under the brand name Nplate among others, is a fusion protein analog of thrombopoietin, a hormone that regulates platelet production...
7 KB (507 words) - 14:56, 14 June 2024
trials demonstrated romiplostim to be effective in treating chronic ITP, especially in relapsed post-splenectomy patients. Romiplostim was approved by the...
51 KB (5,807 words) - 16:34, 18 August 2024
antibodies against endogenous thrombopoietin or lead to thrombosis. Romiplostim (trade name Nplate, formerly AMG 531) was found to be safe and effective...
32 KB (2,879 words) - 14:41, 24 August 2024
maturation of megakaryocytes. Some of them are currently in clinical use: romiplostim, eltrombopag, oprelvekin (a recombinant interleukin 11) and thrombopoietin...
776 bytes (57 words) - 05:54, 29 November 2023
Neupogen (granulocyte colony-stimulating factor) for neutropenia Nplate (romiplostim) for chronic immune thrombocytopenic purpura (FDA approved 2008) Otezla...
96 KB (7,758 words) - 18:19, 12 September 2024
inhibitors: Agerafenib SCF (c-Kit) See here instead. Thrombopoietin Agonists: Eltrombopag Pegacaristim Promegapoietin Romiplostim Thrombopoietin (THPO, MGDF)...
35 KB (3,954 words) - 16:22, 8 September 2024
production by stimulating the receptor for the hormone thrombopoietin; Romiplostim and Eltrombopag are examples. Thrombopoietin mimetics are a type of thrombopoietic...
968 bytes (76 words) - 19:17, 11 February 2022
inhibitors: Agerafenib SCF (c-Kit) See here instead. Thrombopoietin Agonists: Eltrombopag Pegacaristim Promegapoietin Romiplostim Thrombopoietin (THPO, MGDF)...
26 KB (2,203 words) - 04:53, 15 September 2024
inhibitors: Agerafenib SCF (c-Kit) See here instead. Thrombopoietin Agonists: Eltrombopag Pegacaristim Promegapoietin Romiplostim Thrombopoietin (THPO, MGDF)...
62 KB (6,845 words) - 18:30, 22 August 2024
inhibitors: Agerafenib SCF (c-Kit) See here instead. Thrombopoietin Agonists: Eltrombopag Pegacaristim Promegapoietin Romiplostim Thrombopoietin (THPO, MGDF)...
36 KB (3,044 words) - 22:30, 11 September 2024