• Thumbnail for CUL4B
    Cullin-4B is a protein that in humans is encoded by the CUL4B gene which is located on the X chromosome. CUL4B has high sequence similarity with CUL4A, with which...
    23 KB (2,948 words) - 23:56, 9 September 2023
  • Thumbnail for DCAF15
    humans is encoded by the DCAF15 gene. DCAF15 forms a complex with CUL4A or CUL4B that has E3 ubiquitin ligase activity and is responsible for the proteasome...
    965 bytes (144 words) - 06:15, 28 March 2022
  • HGNC:2552 Q13617 3792 CUL3 HGNC:2553 Q13618 3793 CUL4A HGNC:2554 Q13619 3794 CUL4B HGNC:2555 Q13620 3795 CUL5 HGNC:2556 Q93034 3796 CUL7 HGNC:21024 Q14999...
    277 KB (17 words) - 18:34, 6 October 2024
  • Thumbnail for Xeroderma pigmentosum
    larger subunit DDB1 primarily functions as a core component of CUL4A- and CUL4B-based E3 ubiquitin ligase complexes. Substrates that are ubiquitinnated...
    30 KB (3,013 words) - 19:58, 29 October 2024
  • Thumbnail for DDB1
    found that DDB1 primarily functions as a core component of the CUL4A- and CUL4B-based E3 ubiquitin ligase complexes. DDB1 serves as a bridge or adaptor...
    12 KB (1,415 words) - 16:33, 23 December 2023
  • Thumbnail for CUL4A
    cullin family of ubiquitin ligase proteins and is highly homologous to the CUL4B protein. CUL4A regulates numerous key processes such as DNA repair, chromatin...
    36 KB (4,418 words) - 03:28, 3 December 2023
  • Thumbnail for Cullin
    complex (Elongin C - CUL2 - SOCS-box) CUL3, part of CUL3-BTB complex CUL4A CUL4B CUL5 CUL7 CUL9, also known as PARC There is also a more distant member called...
    7 KB (718 words) - 21:57, 20 September 2023
  • Thumbnail for DDB2
    protein-containing complex binding Cellular component nucleoplasm cell junction Cul4B-RING E3 ubiquitin ligase complex nucleus Cul4-RING E3 ubiquitin ligase complex...
    16 KB (2,071 words) - 18:17, 2 October 2024
  • Thumbnail for DTL (gene)
    microtubule organizing center nucleolus Cul4A-RING E3 ubiquitin ligase complex Cul4B-RING E3 ubiquitin ligase complex cytoskeleton nucleus nucleoplasm cytoplasm...
    4 KB (486 words) - 21:43, 20 February 2024
  • Thumbnail for CAND1
    CAND1 gene. CAND1 has been shown to interact with: CUL1, CUL2, CUL3, CUL4A, CUL4B, DCUN1D1, and RBX1. GRCh38: Ensembl release 89: ENSG00000111530 – Ensembl...
    7 KB (959 words) - 22:02, 2 December 2023