Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and anion channel in vertebrates that is encoded by the CFTR gene. Geneticist...
60 KB (6,439 words) - 22:22, 18 August 2024
in both copies (alleles) of the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Those with a single working copy...
161 KB (18,074 words) - 15:46, 26 August 2024
Sionna Therapeutics, for the development of a new cystic fibrosis transmembrane conductance regulator (CFTR) modulators, a type of therapy that treats...
11 KB (957 words) - 22:06, 2 January 2024
Elexacaftor/tezacaftor/ivacaftor (category Cystic fibrosis)
years and older with cystic fibrosis who have at least one F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which...
38 KB (3,107 words) - 08:02, 24 June 2024
Pancreatic disease (section Cystic fibrosis)
and early death. It is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The product of this gene helps create...
8 KB (843 words) - 18:23, 26 October 2023
Ivacaftor (category Cystic fibrosis)
medication used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene (primarily...
34 KB (3,157 words) - 19:11, 14 June 2024
usual function. For example, cystic fibrosis is caused by a defective cystic fibrosis transmembrane conductance regulator (CFTR) protein, and in amyotrophic...
62 KB (4,598 words) - 09:51, 31 July 2024
Inflammatory cytokine (section In cystic fibrosis)
patients with cystic fibrosis show signs of asthma, possibly due to the primary deficiency in the cystic fibrosis transmembrane conductance regulator (CFTR)...
20 KB (2,259 words) - 11:36, 29 July 2024
Pyocyanin (section Cystic fibrosis)
Welsh M, Robertson A (2001). "Regulation of the cystic fibrosis transmembrane conductance regulator ClK channel by its R domain". Journal of Biological...
17 KB (1,971 words) - 18:28, 5 February 2024
the cystic fibrosis transmembrane conductance regulator. Secretin and VIP act to increase the opening of the cystic fibrosis transmembrane conductance regulator...
50 KB (5,610 words) - 14:40, 4 August 2024