• Polyadenylation is the addition of a poly(A) tail to an RNA transcript, typically a messenger RNA (mRNA). The poly(A) tail consists of multiple adenosine...
    57 KB (7,094 words) - 23:56, 6 August 2024
  • Thumbnail for Mature messenger RNA
    of a mature mRNA molecule occurs in 3 steps: Capping of the 5' end Polyadenylation of the 3' end RNA Splicing of the introns During capping, a 7-methylguanosine...
    6 KB (596 words) - 20:39, 4 September 2024
  • Thumbnail for Three prime untranslated region
    Regulatory regions within the 3′-untranslated region can influence polyadenylation, translation efficiency, localization, and stability of the mRNA. The...
    20 KB (2,555 words) - 11:24, 22 February 2024
  • Thumbnail for SV40
    SV40 is an abbreviation for simian vacuolating virus 40 or simian virus 40, a polyomavirus that is found in both monkeys and humans. Like other polyomaviruses...
    19 KB (2,245 words) - 17:21, 17 September 2024
  • Cleavage and polyadenylation specificity factor (CPSF) is involved in the cleavage of the 3' signaling region from a newly synthesized pre-messenger RNA...
    15 KB (1,894 words) - 16:46, 28 November 2023
  • Thumbnail for Messenger RNA
    early stop codon, which, upon translation, produces a shorter protein. Polyadenylation is the covalent linkage of a polyadenylyl moiety to a messenger RNA...
    49 KB (5,922 words) - 14:24, 18 August 2024
  • Thumbnail for Post-transcriptional modification
    tail. The cleavage and adenylation reactions occur primarily if a polyadenylation signal sequence (5'- AAUAAA-3') is located near the 3' end of the pre-mRNA...
    11 KB (1,432 words) - 23:35, 24 July 2024
  • Thumbnail for CPEB
    CPEB, or cytoplasmic polyadenylation element binding protein, is a highly conserved RNA-binding protein that promotes the elongation of the polyadenine...
    19 KB (2,236 words) - 21:48, 18 August 2024
  • The cytoplasmic polyadenylation element (CPE) is a sequence element found in the 3' untranslated region of messenger RNA. While several sequence elements...
    9 KB (1,178 words) - 13:13, 22 February 2024
  • Thumbnail for U1A polyadenylation inhibition element (PIE)
    The U1A polyadenylation inhibition element (PIE) is an RNA element which is responsible for the regulation of the length of the polyA tail of the U1A...
    2 KB (175 words) - 17:50, 16 January 2022