The type-I interferons (IFN) are cytokines which play essential roles in inflammation, immunoregulation, tumor cells recognition, and T-cell responses...
24 KB (2,932 words) - 03:26, 14 June 2024
on the type of receptor through which they signal, human interferons have been classified into three major types. Interferon type I: All type I IFNs bind...
62 KB (7,065 words) - 05:17, 28 June 2024
are three known types of interferon. With approximately 450 genes highly expressed in response to interferon type I. Type I interferon consists of INF-α...
13 KB (1,530 words) - 20:52, 19 April 2024
respond to a select group of cytokines including interferon type I, interferon type II, interferon type III. and members of the interleukin-10 family These...
6 KB (616 words) - 18:29, 7 June 2023
Interferon gamma (IFNG or IFN-γ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. The existence of this interferon...
56 KB (6,476 words) - 06:27, 13 September 2024
The type III interferon group is a group of anti-viral cytokines, that consists of four IFN-λ (lambda) molecules called IFN-λ1, IFN-λ2, IFN-λ3 (also known...
12 KB (1,397 words) - 15:30, 12 June 2024
type I interferon production when cells are infected with intracellular pathogens, such as viruses, mycobacteria and intracellular parasites. Type I interferon...
24 KB (2,748 words) - 06:07, 21 September 2024
The interferon-α/β receptor (IFNAR) is a virtually ubiquitous membrane receptor which binds endogenous type I interferon (IFN) cytokines. Endogenous human...
24 KB (2,617 words) - 19:43, 7 August 2022
recently reviewed. There are 3 types of IFNs: Interferon type I, Interferon type II and Interferon type III. The type II IFN, also called IFNγ, is produced...
20 KB (2,608 words) - 08:06, 11 January 2024
'movement'. Interferon-alpha, an interferon type I, was identified in 1957 as a protein that interfered with viral replication. The activity of interferon-gamma...
35 KB (3,965 words) - 16:19, 27 September 2024