• Thumbnail for Sunitinib
    Sunitinib, sold under the brand name Sutent, is an anti-cancer medication. It is a small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor...
    36 KB (3,447 words) - 05:37, 9 August 2024
  • Thumbnail for Pancreatic neuroendocrine tumor
    effectiveness of everolimus in carcinoid tumors have not been established. sunitinib (Sutent) is labeled for treatment of progressive, well-differentiated...
    28 KB (2,471 words) - 07:39, 19 October 2024
  • cytokine therapy (IL-2, interferon), kinase inhibitors (temsirolimus, sunitinib, sorafenib, pazopanib) and anti-angiogenic therapies (bevacizumab). "Clear...
    3 KB (333 words) - 01:07, 3 December 2023
  • (NSCLC). Sunitinib is an oral drug that inhibits the phosphorylation of all the VEGF receptors, PDGFR-ß, KIT FLT3, CSF1R and GDNF. Sunitinib is used in...
    51 KB (4,735 words) - 08:15, 2 January 2024
  • shut down in 2003, after developing the pioneering kinase inhibitor drug sunitinib (Sutent). Sugen was founded in 1991 in Redwood City, California, by veteran...
    8 KB (823 words) - 17:00, 26 September 2024
  • small molecules that inhibit the tyrosine kinases stimulated by VEGF: sunitinib, sorafenib, axitinib, and pazopanib (some of these therapies target VEGF...
    14 KB (1,693 words) - 18:18, 18 October 2024
  • Thumbnail for Tyrosine kinase inhibitor
    inhibitor that is effective both as a senolytic and as therapy for CML. Sunitinib, an inhibitor of the receptors for FGF, PDGF and VEGF is also based on...
    10 KB (1,179 words) - 18:31, 8 August 2024
  • Thumbnail for Toceranib
    phosphate. It was developed by SUGEN as SU11654, a sister compound to sunitinib, which was later approved for human therapies. Toceranib is a tyrosine...
    7 KB (374 words) - 00:31, 1 July 2024
  • Thumbnail for Zanzalintinib
    randomized study of zanzalintinib in combination with nivolumab versus sunitinib in patients with advanced or metastatic non-clear cell RCC (nccRCC). Sharma...
    5 KB (188 words) - 12:33, 5 September 2024
  • Thumbnail for Gastrointestinal stromal tumor
    tyrosine kinase inhibitor sunitinib (marketed as Sutent) can be considered.: 26 and 31  The effectiveness of imatinib and sunitinib depend on the genotype...
    43 KB (4,502 words) - 18:59, 16 July 2024