• Thumbnail for ATF4
    (tax-responsive enhancer element B67), also known as ATF4, is a protein that in humans is encoded by the ATF4 gene. This gene encodes a transcription factor...
    15 KB (1,773 words) - 00:39, 27 September 2024
  • complex called translation initiation factor 2 (eIF2), resulting in the gene ATF4 being turned on, which will further affect gene expression. eIF2 consists...
    13 KB (1,625 words) - 20:23, 3 December 2023
  • factors before it can carry out translation of the main protein. For example, ATF4 regulation is performed by two uORFs further upstream, named uORF1 and uORF2...
    21 KB (2,428 words) - 20:42, 3 June 2024
  • transcription factors, specifically ATF4, can influence how readily a neuron undergoes cell death. The presence of ATF4 promotes resistance in cells against...
    24 KB (2,638 words) - 00:26, 29 August 2024
  • Thumbnail for DISC1
    DISC1 (section ATF4/ATF5)
    namely Alzheimer's disease, Parkinson's disease, and Huntington's disease. ATF4 and ATF5 are members of the leucine zipper activating transcription factor...
    39 KB (4,723 words) - 06:28, 29 March 2024
  • Thumbnail for Spilanthol
    spilanthol inhibits the activation of several transcription factors (NFκB, ATF4, FOXO1, IRF1, ETS1, and AP-1) which may explain the effect of spilanthol...
    5 KB (454 words) - 15:39, 7 August 2024
  • Thumbnail for CREB
    genes encode CREB or CREB-like proteins: CREB1 (CREB1) CREB2 renamed ATF4 (ATF4) CREB3 (CREB3) CREB5 (CREB5) CREB3L1 (CREB3L1) CREB3L2 (CREB3L2) CREB3L3...
    19 KB (2,243 words) - 23:46, 9 September 2024
  • they have in maintaining homeostasis. Some of these ATFs, such as ATF3, ATF4, and ATF6 are known to play a role in stress responses. Another example of...
    3 KB (319 words) - 04:00, 16 August 2023
  • Thumbnail for Chromosome 22
    ASCC2: encoding protein activating signal cointegrator 1 complex subunit 2 ATF4 (22q13) encoding protein cyclic AMP-dependent transcription factor ATF-4...
    27 KB (2,209 words) - 17:18, 18 August 2024
  • Thumbnail for Tomatidine
    reducing weakness and atrophy in aged skeletal muscle by interaction with the ATF4 (a critical mediator of age-related muscle weakness and atrophy). Dietary...
    6 KB (537 words) - 15:28, 26 February 2024