Biliverdin reductase B is a protein that in humans is encoded by the BLVRB gene. The BLVRB gene was localized to chromosome 19, the specific region being...

Biliverdin reductase (BVR) is an enzyme (EC 1.3.1.24) found in all tissues under normal conditions, but especially in reticulo-macrophages of the liver...

The production of biliverdin from heme is the first major step in the catabolic pathway, after which the enzyme biliverdin reductase performs the second...

on NADPH-cytochrome P450 reductase and oxygen to cleave heme/porphyrin ring at the alpha-methene bridge to form biliverdin (or verdoglobin if the heme...

generated from the degradation of heme, which is first degraded through biliverdin to bilirubin. Bilirubin is then excreted as bile, which is further degraded...

Macrophages break down senescent erythrocytes and break the heme down into biliverdin, which rapidly reduces to free bilirubin. Bilirubin binds tightly to plasma...

Ennis O, Mantle TJ (1 Jun 1996). "Evidence that biliverdin-IX beta reductase and flavin reductase are identical". Biochem. J. 316 (2): 385–7. doi:10...

to biliverdin and well as carbon monoxide that is exhaled. Biliverdin is then converted to bilirubin with biliverdin reductase. As high biliverdin levels...

its damaging effects. In the second reaction, biliverdin is converted to bilirubin by biliverdin reductase (BVR): Bilirubin is transported into the liver...

color tetrapyrrole pigment called bilirubin by cytosolic enzyme biliverdin reductase. This bilirubin is "unconjugated", "free", or "indirect" bilirubin...