CD27 is a member of the tumor necrosis factor receptor superfamily. It is currently of interest to immunologists as a co-stimulatory immune checkpoint...
10 KB (1,133 words) - 04:35, 22 December 2023
superfamily—CD27, CD40, OX40, GITR and CD137. Another two stimulatory checkpoint molecules belong to the B7-CD28 superfamily—CD28 itself and ICOS. CD27: This...
31 KB (3,467 words) - 01:27, 25 June 2024
that in humans is encoded by CD70 gene. CD70 is also known as a ligand for CD27. In physiological condition the expression of CD70 on immune cells is transient...
10 KB (1,089 words) - 22:01, 21 December 2023
receptor. In humans, CD27 is a good marker for plasma cells; naïve B cells are CD27−, memory B-cells are CD27+ and plasma cells are CD27++. The surface antigen...
24 KB (2,793 words) - 18:41, 30 May 2024
promote the secretion of immunoglobulins though CD27/CD70 interactions. B cells begin expressing CD27 at the beginning of the centroblast stage and lose...
6 KB (636 words) - 06:08, 7 July 2024
CD226 or CRTAM) and TNF receptor super-family (TNFRSF) (such as 41-BB, OX40, CD27, GITR, HVEM, CD40, BAFFR, BAFF and others). Additionally, some co-stimulatory...
15 KB (1,920 words) - 19:42, 24 February 2024
umbilical cord and adult peripheral blood express the novel phenotype CD20+CD27+CD43+CD70 in the Journal of Experimental Medicine. He is senior fellow in...
17 KB (1,622 words) - 03:29, 14 May 2024
receptors (BCR), high levels of IgM, Toll-like receptors (TLRs), CD21, CD1, CD9, CD27 with low to negligible levels of secreted-IgD, CD23, CD5, and CD11b that...
12 KB (1,506 words) - 08:04, 23 October 2023
Election Returns: District Definitions California Voter Foundation map - CD27 34°15′54″N 117°56′06″W / 34.26500°N 117.93500°W / 34.26500; -117.93500...
61 KB (592 words) - 17:35, 25 June 2024
distinguished by the cell surface marker CD27, although some subsets do not express CD27. Memory B cells that lack CD27 are generally associated with exhausted...
24 KB (3,168 words) - 14:40, 30 April 2024