CRISPR interference (CRISPRi) is a genetic perturbation technique that allows for sequence-specific repression of gene expression in prokaryotic and eukaryotic...

the re-engineering of the metabolic pathways of E. coli by CRISPR and CRISPRi systems toward the production of a chemical known as 1,4-butanediol, which...

to introduce disruptive insertions or deletions. CRISPR interference (CRISPRi) on the other hand utilizes a catalytically inactive nuclease to physically...

"Targeted regulation of transcription in primary cells using CRISPRa and CRISPRi". Genome Res. 31 (11): 2120–2130. doi:10.1101/gr.275607.121. PMC 8559706...

RNAi. Although CRISPRi/a cannot replace genome editing in all experiments, they can act as effective alternatives in some cases. CRISPRi and CRISPRa use...

endonuclease activity (dCas9), which is the basis for CRISPR interference (CRISPRi). His laboratory subsequently developed CRISPR-Genome Organization (CRISPR-GO)...

CRISPR-Cas10 - CRISPR-Cas13 - CRISPR-BEST CRISPR-Disp - CRISPR-Gold - CRISPRa - CRISPRi Easi-CRISPR - FACE Enzyme Cas9 - FokI - EcoRI - PstI - SmaI HaeIII - Cas12a...

phenotype of interest. Apart from knock-out there are also knock-down (CRISPRi) and activation (CRISPRa) libraries, which using the ability of proteolytically...

PMID 27084023. Dhamad AE, Lessner DJ (October 2020). Atomi H (ed.). "A CRISPRi-dCas9 System for Archaea and Its Use To Examine Gene Function during Nitrogen...

Wang X, Lim WA, Weissman JS, Qi LS (November 2013). "CRISPR interference (CRISPRi) for sequence-specific control of gene expression". Nature Protocols. 8...