In humans, clusterin (CLU) is encoded by the CLU gene on chromosome 8. CLU is an extracellular molecular chaperone which binds to misfolded proteins in...
22 KB (2,433 words) - 05:09, 24 January 2024
APOE), presenilin 1 (PSEN1), bridging Integrator 1 (BIN1), SORL1, and Clusterin (CLU) genes increasing one's risk to develop the condition. However, research...
57 KB (6,147 words) - 15:28, 12 June 2024
Liberation – University Czech Lacrosse Union CLU (gene), the gene for clusterin CLU (programming language) Clu (Tron), fictional character from the Tron...
756 bytes (107 words) - 07:50, 16 May 2024
genes. Antiapoptotic proteins, such as clusterin and survivin, are often expressed in cancer cells. Clusterin and survivin-targeting siRNAs were used...
48 KB (5,609 words) - 06:40, 12 September 2024
B-cell activating factor 4-1BB ligand Cholesterylester transfer protein Clusterin Colony-stimulating factor Hemopexin Lactoferrin Membrane glycoproteins...
36 KB (4,018 words) - 18:24, 24 September 2024
complexes do not bind to cell membranes and are ultimately scavenged by clusterin and vitronectin, two regulators of complement. The membrane attack complex...
9 KB (1,061 words) - 05:28, 8 January 2024
can be diagnosed by checking the levels of several biomarkers such as clusterin and cystatin C. While the duration of ischemia was used as a biomarker...
39 KB (4,566 words) - 04:02, 24 August 2024
the complement cascade, the formation of the membrane attack complex. Clusterin, a soluble molecule with functions similar to CD59, forms a complex with...
26 KB (3,061 words) - 14:02, 25 September 2024
treatment of cancer. It is an antisense oligonucleotide (ASO) targeting clusterin expression. In metastatic prostate cancer, custirsen showed no benefit...
11 KB (1,232 words) - 18:46, 1 July 2024
C10 C11 C13 C14 C19 Hsp70 1A 1B 1L 2 4 4L 5 6 7 8 9 12A 14 Hsp90 α1 α2 β ER TRAP1 Other Alpha crystallin Clusterin Survival of motor neuron SMN1 SMN2...
97 KB (11,021 words) - 17:45, 18 September 2024