G1/S-specific cyclin-E1 is a protein that in humans is encoded by the CCNE1 gene. The protein encoded by this gene belongs to the highly conserved cyclin family...

and cyclin E1. By inhibiting mir-424 in normal endothelial cells they could observe the same increased protein expression of MEK1 and cyclin E1 which...

A cyclin-dependent kinase inhibitor protein (also known as CKIs, CDIs, or CDKIs) is a protein that inhibits the enzyme cyclin-dependent kinase (CDK) and...

transcription factor. Cyclin-dependent kinase 2 has been shown to interact with: BRCA1, CDK2AP1, CDKN1B CDKN3, CEBPA, Cyclin A1, Cyclin E1, Flap structure-specific...

promote entry into S phase. Eukaryotic cells possess two types of cyclin, cyclin E1 and cyclin E2, with the protein sequences sharing 69.3% similarity in humans...

Cyclin E is a member of the cyclin family. Cyclin E binds to G1 phase Cdk2, which is required for the transition from G1 to S phase of the cell cycle...

Palbociclib is less effective in patients whose breast cancer cells overexpress cyclin E1 or E2, and Brk (breast tumor-related kinase). Brk is an intracellular...

cell cycle progression through Cyclin E1. More specifically, DDX3X was shown to directly bind to the 5´ UTR of Cyclin E1, thereby facilitating the protein's...

receptors and Wilm tumor suppressor 1. The CCNE1 gene encodes for the cyclin E1 protein which accumulates at the G1-S phase transition point of the cell...

V.; Cook, A.; Brown, N. R.; Johnson, L. N. (2005). "The structure of cyclin E1/CDK2: Implications for CDK2 activation and CDK2-independent roles". The...