Deoxyribonuclease I (usually called DNase I), is an endonuclease of the DNase family coded by the human gene DNASE1. DNase I is a nuclease that cleaves...
11 KB (1,397 words) - 22:17, 3 August 2024
Deoxyribonuclease (DNase, for short) refers to a group of glycoprotein endonucleases which are enzymes that catalyze the hydrolytic cleavage of phosphodiester...
26 KB (3,220 words) - 16:37, 6 November 2023
Dornase alfa (category Articles without InChI source)
for the treatment of cystic fibrosis. It is a recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA. Dornase alfa...
4 KB (227 words) - 00:23, 8 January 2024
within a polynucleotide chain (namely DNA or RNA). Some, such as deoxyribonuclease I, cut DNA relatively nonspecifically (without regard to sequence)...
25 KB (2,688 words) - 21:18, 6 April 2024
encodes a member of the deoxyribonuclease family and the protein and DNA shows high sequence similarity to lysosomal DNase I. Alternate transcriptional...
14 KB (1,676 words) - 02:39, 4 January 2024
chromatin-bound proteins, the other three are commonly used for: mapping Deoxyribonuclease I hypersensitive sites (DHSs), sequencing the DNA unbound by chromatin...
39 KB (4,420 words) - 19:10, 15 May 2024
crystallization, by Moses Kunitz in 1948, of a DNA depolymerase (deoxyribonuclease I), and precise work by Rollin Hotchkiss showing that virtually all...
22 KB (2,581 words) - 14:06, 24 April 2024
variable number of tandem repeat polymorphisms within the human deoxyribonuclease I gene". Legal Medicine. 17 (4): 283–6. doi:10.1016/j.legalmed.2015...
20 KB (2,011 words) - 06:29, 6 August 2024
human deoxyribonuclease I (DNase I), that Protalix has designed, through chemical modification, to be resistant to inhibition by actin. DNase I is part...
14 KB (1,331 words) - 06:22, 3 April 2023
Deoxyribonuclease gamma is an enzyme that in humans is encoded by the DNASE1L3 gene. This gene encodes a member of the DNase family. The protein hydrolyzes...
6 KB (724 words) - 22:07, 3 March 2023