4 G (eIF4G) is a protein involved in eukaryotic translation initiation and is a component of the eIF4F cap-binding complex. Orthologs of eIF4G have been...
8 KB (1,074 words) - 01:25, 9 January 2023
protein which triggers the binding of eukaryotic initiation factor 4 complex (eIF4G) directly to the poly(A) tail of mRNA which is 200-250 nucleotides long...
15 KB (1,980 words) - 07:45, 17 February 2024
eIF4A, the cap-binding protein eIF4E, and the large "scaffold" protein eIF4G. The mammalian eIF4F complex was first described in 1983, and has been a...
7 KB (683 words) - 21:17, 6 October 2024
end of rotavirus mRNAs and is coimmunoprecipitated with eIF4G. The binding of NSP3A to eIF4G and its specific interaction with the 3' end of viral mRNA...
3 KB (317 words) - 19:07, 27 September 2022
which consists of three other initiation factors: eIF4A, eIF4E, and eIF4G. eIF4G is a scaffolding protein that directly associates with both eIF3 and...
15 KB (1,859 words) - 06:18, 27 May 2024
stem-loops that radiate from a central hub. BTE has been found to bind to eIF4G and weakly to eIF4E (proteins involved in translation initiation). BTE allows...
3 KB (279 words) - 00:22, 28 February 2024
intact eIF4G for IRES initiation is specific to HAV IRES among other picornaviruses. eIF4E-binding protein I (4E-BP1) will also interfere with the eIF4G protein...
13 KB (1,701 words) - 02:06, 1 December 2023
such as poliovirus, this is accomplished by viral proteolytic cleavage of eIF4G so that it cannot interact with the 5'cap binding protein eIF4E. Interaction...
19 KB (1,775 words) - 04:06, 27 May 2024
of translation, the CBC is replaced by the translation factors eIF4E and eIF4G of the eIF4F complex. This complex is then recognized by other translation...
16 KB (1,873 words) - 16:18, 29 June 2024
isothermal titration calorimetry documented that NSP3 and PABP use analogous eIF4G recognition strategies, despite marked differences in tertiary structure...
4 KB (478 words) - 18:24, 12 April 2024