Transcription factor GATA-4 is a protein that in humans is encoded by the GATA4 gene. This gene encodes a member of the GATA family of zinc finger transcription...

recruiting corepressors. There is also evidence that GATA binding protein 4 (GATA4) and FOG2 contribute to activation of SRY by associating with its promoter...

disease are caused by Kozak sequence mutations in the GATA4 gene's 5' untranslated region. The GATA4 gene is responsible for gene expression in a wide variety...

protein. Gata4 is an essential gene responsible for cardiac morphogenesis. It also regulates the gene expression of hspb7 and hspb12. Gata4 depletion...

is specified early in development by Gata4 expression, and Gata4 goes on to direct gut morphogenesis later. Gata4 expression is controlled in the early...

other proteins that bind to it for selective autophagy. By interacting with GATA4 and targeting it for degradation, it can inhibit GATA-4 associated senescence...

determination by downstream regulation of sex-determining factors (such as GATA4, SOX9 and AMH), which lead to development of the male phenotype, including...

MYH6 are also associated with cardiac defects. The transcription factor GATA4 forms a complex with the TBX5 which interacts with MYH6. Another factor...

TOF cases. ZFPM2 is another cardiac regulator involved in regulation of GATA4. Mutations of the ZFPM2 gene lead to reduced GATA production and have been...

Prostate cancer GSTP1, MYC, PTEN, APC, PCA3, PSMA, AMACR, BRCA1, BRCA2 Colorectal cancer KRAS, BRAF, PIK3CA, TP53, APC, SFRP2, ITGA4, GATA4, GATA5, OSMR...