The γ-hydroxybutyrate (GHB) receptor (GHBR), originally identified as GPR172A, is an excitatory G protein-coupled receptor (GPCR) that binds the neurotransmitter...
12 KB (1,348 words) - 02:36, 28 March 2024
Γ-Hydroxybutyric acid (redirect from Ghb)
glycine in certain brain areas. It acts on the GHB receptor and is a weak agonist at the GABAB receptor. GHB has been used in the medical setting as a general...
89 KB (9,448 words) - 10:19, 5 October 2024
Γ-Butyrolactone (category GHB receptor agonists)
acts as a prodrug for gamma-hydroxybutyric acid (GHB) and is often used as a recreational drug. GHB acts as a central nervous system (CNS) depressant...
31 KB (3,122 words) - 10:14, 2 November 2024
GABA analogue (category GABA receptor agonists)
GHB receptor agonist UMB68 (γ-hydroxy-γ-methylpentanoic acid) – synthetic GHB receptor agonist GABOB (β-hydroxy-GABA) – anticonvulsant; GABA receptor...
8 KB (754 words) - 04:40, 27 January 2024
1,4-Butanediol (category GHB receptor agonists)
gamma-hydroxybutyrate (GHB), but several other federal courts have ruled that it does not. Butane-1,4-diol is rapidly converted into GHB acid by the enzymes...
19 KB (1,832 words) - 01:00, 22 October 2024
4-Hydroxy-4-methylpentanoic acid (category GHB receptor agonists)
been shown to bind selectively to the GHB receptor ligand in binding assays, yet does not bind to GABAergic receptors. As such, it can provide a useful tool...
3 KB (136 words) - 04:34, 25 March 2024
(GHV) GHB receptor antagonists: NCS-382 Gabazine Some GHB receptors modulators only bind to the GHB receptor, while others bind to both the GHB and GABAB...
130 KB (13,432 words) - 06:24, 11 September 2024
Gabazine (category GHB receptor antagonists)
GABAA receptors, which may represent the GHB receptor. Behrens CJ, van den Boom LP, Heinemann U (April 2007). "Effects of the GABA(A) receptor antagonists...
4 KB (324 words) - 20:53, 23 September 2024
The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline)...
33 KB (2,982 words) - 11:42, 7 August 2024
Sulpiride (category GHB receptor ligands)
gamma-hydroxybutyrate receptor in vivo at therapeutic concentrations. Sulpiride was found in one study in rats to upregulate GHB receptors. GHB has neuroleptic...
30 KB (2,751 words) - 07:29, 22 October 2024