• Thumbnail for MAD2L1
    checkpoint protein MAD2A is a protein that in humans is encoded by the MAD2L1 gene. MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents...
    16 KB (1,975 words) - 22:35, 3 March 2023
  • Thumbnail for Insulin receptor
    Insulin receptor has been shown to interact with ENPP1, GRB10, GRB7, IRS1, MAD2L1, PRKCD, PTPN11, and SH2B1. GRCh38: Ensembl release 89: ENSG00000171105 –...
    31 KB (3,785 words) - 19:26, 2 September 2024
  • Thumbnail for HORMA domain
    integrity. Humans proteins containing this domain include: HORMAD1, HORMAD2, MAD2L1, MAD2L2 He X, Patterson TE, Sazer S (1997). "The Schizosaccharomyces pombe...
    2 KB (202 words) - 14:31, 7 June 2023
  • Thumbnail for MAD2L1BP
    MAD2L1-binding protein is a protein that in humans is encoded by the MAD2L1BP gene. The protein encoded by this gene was identified as a binding protein...
    6 KB (823 words) - 23:25, 3 March 2023
  • Thumbnail for MAD1L1
    the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Some...
    8 KB (644 words) - 00:00, 3 December 2023
  • confer sensitivity to microtubule poisons. The human orthologues of Mad2 (MAD2L1 and MAD2L2) were first cloned in a search for human cDNAs that would rescue...
    10 KB (1,150 words) - 15:42, 12 April 2024
  • O75367 9084 MACROH2A2 HGNC:14453 Q9P0M6 9085 MAD1L1 HGNC:6762 Q9Y6D9 9086 MAD2L1 HGNC:6763 Q13257 9087 MAD2L1BP HGNC:21059 Q15013 9088 MAD2L2 HGNC:6764 Q9UI95...
    277 KB (17 words) - 18:41, 6 October 2024
  • Thumbnail for CDC20
    interact with: ANAPC7 BUB1B, CDC16, CDC27, Cyclin A1, FBXO5, HDAC1, HDAC2, and MAD2L1. However, the most important interaction of CDC20 is with the Anaphase Promoting...
    26 KB (3,307 words) - 16:24, 13 October 2024
  • Thumbnail for MAD2L2
    the metaphase plate. MAD2L2 is a homolog of MAD2L1. MAD2L2 has been shown to interact with: ADAM9, MAD2L1, REV1, and REV3L. GRCh38: Ensembl release 89:...
    8 KB (1,003 words) - 22:38, 27 December 2023
  • Thumbnail for NEK2
    of mitotic checkpoint protein complex via phosphorylation of CDC20 and MAD2L1. Plays an active role in chromatin condensation during the first meiotic...
    9 KB (1,182 words) - 23:52, 12 September 2024