The minimal genome is a concept which can be defined as the set of genes sufficient for life to exist and propagate under nutrient-rich and stress-free...

inception. Initially the goal was to identify a minimal set of genes that are required to sustain life from the genome of Mycoplasma genitalium, and rebuild these...

There is experimental work being done on minimal genomes for single cell organisms as well as minimal genomes for multi-cellular organisms (see developmental...

(13% of the genome size) of all sequenced bacterial genomes at the time of its publication (2004). In 2010, as part of the Minimal Genome Project, a team...

for biological functions. The small genome of M. genitalium made it the organism of choice in The Minimal Genome Project, a study to find the smallest...

essential genes (~10% of their genes). The synthetic organism, Syn 3, has a minimal genome of 473 essential genes and quasi-essential genes (necessary for fast...

minimal genomes from which new strains can be developed. These minimal strains provide a near guarantee that experiments on genes outside the minimal...

biotechnology. The formation of animals with a chemically manufactured (minimal) genome is another facet of synthetic biology that is highlighted by synthetic...

PG21 genome sequence shows that this organism is the second smallest genome among self-replicating free living organisms. Due to their minimal genomes, M...

Genome-wide CRISPR-Cas9 knockout screens aim to elucidate the relationship between genotype and phenotype by ablating gene expression on a genome-wide...