Nusinersen, marketed as Spinraza, is a medication used in treating spinal muscular atrophy (SMA), a rare neuromuscular disorder. In December 2016, it became...
27 KB (2,095 words) - 15:28, 26 September 2024
outcomes. Medications that target the genetic cause of the disease include nusinersen, risdiplam, and the gene therapy medication onasemnogene abeparvovec....
89 KB (9,953 words) - 13:12, 2 October 2024
therapeutics. The company has three commercially approved medicines: Spinraza (Nusinersen), Tegsedi (Inotersen), and Waylivra (Volanesorsen), and has four drugs...
16 KB (1,428 words) - 12:29, 20 September 2024
increase in the concentration of the functional SMN protein in vivo. Nusinersen, the first drug approved to treat SMA, an anti-sense oligonucleotide targeting...
23 KB (1,786 words) - 09:06, 12 August 2024
oligonucleotide later named nusinersen was developed by Ionis Pharmaceuticals under a licensing agreement with Biogen. In December 2016, nusinersen received regulatory...
23 KB (2,219 words) - 02:24, 20 August 2024
M09AX04 Drisapersen M09AX05 Aceneuramic acid M09AX06 Eteplirsen M09AX07 Nusinersen M09AX08 Golodirsen M09AX09 Onasemnogene abeparvovec M09AX10 Risdiplam...
1 KB (248 words) - 05:17, 18 December 2023
(INN) Nulytely Numax Numorphan nupafant (INN) Nuprin Nurofen Nuromax nusinersen (INN) Nutracort Nutrestore Nutrilipid Nutropin Nutropin AQ Nuvaring nuvenzepine...
6 KB (342 words) - 21:00, 27 August 2024
and National Academy of Sciences member. Adrian R. Krainer, developed nusinersen to treat spinal muscular atrophy (SMA), winner of the Breakthrough Prize...
37 KB (3,981 words) - 17:53, 2 July 2024
Laboratory in Laurel Hollow, New York for the early-stage development of nusinersen. Nusinersen became FDA approved in 2016 as the first treatment for spinal muscular...
41 KB (4,198 words) - 17:12, 9 October 2024
inflammatory bowel disease 2019 2018 Biosimilar of AbbVie's Humira. SPINRAZA (nusinersen) Spinal muscular atrophy (SMA) 2016 2017 The first drug approved for the...
48 KB (3,837 words) - 18:51, 12 September 2024