• Thumbnail for PKM2
    opa-interacting protein 3 (OIP3), is an enzyme that in humans is encoded by the PKM2 gene. PKM2 is an isoenzyme of the glycolytic enzyme pyruvate kinase. Depending...
    38 KB (4,865 words) - 20:29, 3 December 2023
  • Thumbnail for Pyruvate kinase
    the gene PKLR, whereas the M1 and M2 isozymes are expressed by the gene PKM2. The R and L isozymes differ from M1 and M2 in that they are allosterically...
    33 KB (4,042 words) - 02:51, 1 February 2024
  • a synonym for the dimeric form of the pyruvate kinase isoenzyme type M2 (PKM2), a key enzyme within tumor metabolism. Tumor M2-PK can be elevated in many...
    17 KB (2,307 words) - 01:55, 28 March 2024
  • Thumbnail for ARAF
    cells. A-Raf upregulates the activity of PKM2 by promoting a conformational change in PKM2. This causes PKM2 to transition from its low-activity dimeric...
    16 KB (1,985 words) - 12:57, 29 July 2023
  • tumorigenesis. Lu demonstrated that glycolytic enzyme pyruvate kinase M2 (PKM2) acts as a protein kinase and phosphorylates histone H3 to epigenetically...
    18 KB (1,876 words) - 10:49, 20 August 2023
  • Thumbnail for Poznań Junikowo railway station
    towards Zbąszynek Preceding station Poznan Metropolitan Railway (PKM) Following station Palędzie towards Nowy Tomyśl PKM2 Poznań Górczyn towards Września...
    3 KB (209 words) - 22:02, 6 July 2024
  • metabolism was likely to vary across different forms of cancer; however, PKM2 was identified in all of the cancer cells they had tested. This enzyme form...
    25 KB (3,046 words) - 04:10, 10 April 2024
  • Thumbnail for Koleje Wielkopolskie
    following lines:   Poznań Główny – Kutno (Part of Poznań suburban rail Line  PKM2  between Poznań Główny and Września)   Poznań Główny – Mogilno (Part of Poznań...
    9 KB (326 words) - 17:19, 21 June 2023
  • Thumbnail for Tumor metabolome
    type M2 or PKM2 is present in embryonic, adult stem cells. It is also expressed by many tumor cells. The alterations to metabolism by PKM2 increases ATP...
    22 KB (2,576 words) - 03:03, 28 November 2023
  • Bypassing Pyruvate Kinase: Considerations for Cells Exhibiting Dimeric PKM2 or Otherwise Inhibited Kinase Activity, https://www.frontiersin.org/articles/10...
    33 KB (3,705 words) - 17:59, 8 June 2024