Phosphoinositide 3-kinases (PI3Ks), also called phosphatidylinositol 3-kinases, are a family of enzymes involved in cellular functions such as cell growth...

Phosphoinositide 3-kinase inhibitors (PI3K inhibitors) are a class of medical drugs that are mainly used to treat advanced cancers. They function by inhibiting...

the field of biochemistry, PDPK1 refers to the protein 3-phosphoinositide-dependent protein kinase-1, an enzyme which is encoded by the PDPK1 gene in humans...

Class I PI 3-kinases are a subgroup of the enzyme family, phosphoinositide 3-kinase that possess a common protein domain structure, substrate specificity...

Talaromyces wortmannii, is a non-specific, covalent inhibitor of phosphoinositide 3-kinases (PI3Ks). It has an in vitro inhibitory concentration (IC50) of...

received at least two prior systemic therapies. Phosphoinositide 3-kinase Phosphoinositide 3-kinase inhibitor PIK3CA-related overgrowth spectrum P110α...

5)-trisphosphate (PIP3). Akt, a serine/threonine kinase, is recruited to the membrane by interaction with these phosphoinositide docking sites, so that it can be fully...

phosphatidylinositol 3-kinase, and its homologue p85 beta". Oncogene. 7 (4): 789–93. PMID 1314371. "Entrez Gene: PIK3R1 phosphoinositide-3-kinase, regulatory subunit...

that a kinase activity associated with the middle T oncoprotein is a phosphoinositide kinase, that it is a novel type of phosphoinositide kinase that phosphorylates...

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform also known as phosphoinositide 3-kinase (PI3K) delta isoform or p110δ is an...