• Thumbnail for Pleuromutilin
    Pleuromutilin and its derivatives are antibacterial drugs that inhibit protein synthesis in bacteria by binding to the peptidyl transferase component...
    12 KB (1,113 words) - 10:10, 24 August 2023
  • Thumbnail for Tiamulin
    Tiamulin (category Pleuromutilin antibiotics)
    Tiamulin (previously thiamutilin) is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry. Tiamulin is...
    3 KB (96 words) - 08:02, 24 June 2024
  • Thumbnail for Lefamulin
    Lefamulin (category Pleuromutilin antibiotics)
    nausea, pain at the site of injection, and liver inflammation. It is a pleuromutilin antibiotic that inhibits the large subunit of bacterial ribosomes. Lefamulin...
    10 KB (704 words) - 08:01, 24 June 2024
  • in the 23S rRNA of the ribosome and inhibits peptide bond formation. Pleuromutilins also bind to the peptidyl transferase center. Macrolide antibiotics...
    6 KB (682 words) - 07:29, 8 September 2024
  • Thumbnail for Retapamulin
    Retapamulin (category Pleuromutilin antibiotics)
    developed by GlaxoSmithKline. It is the first drug in the new class of pleuromutilin antibiotics to be approved for human use. It is marketed as an ointment...
    5 KB (238 words) - 21:41, 20 December 2023
  • Thumbnail for 9-Borabicyclo(3.3.1)nonane
    Sorensen, E. J. (2011). "A concise synthesis of the molecular framework of pleuromutilin". Chem. Commun. 47 (5): 1500–1502. doi:10.1039/C0CC04077K. PMC 3156455...
    5 KB (391 words) - 05:36, 30 September 2024
  • Thumbnail for Bioprospecting
    polymyxins, cephalosporins and other β-lactam antibiotics, macrolides, pleuromutilins, glycopeptides, rifamycins, lincosamides, streptogramins, and phosphonic...
    63 KB (6,392 words) - 02:44, 9 August 2024
  • tiamulin, and valnemulin are derivatives of the fungal metabolite pleuromutilin. Plectasin, austrocortilutein, austrocortirubin, coprinol, oudemansin...
    19 KB (1,718 words) - 19:43, 22 April 2024
  • Thumbnail for Antibiotic
    targeting bacterial ribosomes). FDA approved on 2 October 2018. Lefamulin: pleuromutilin antibiotic. FDA approved on 19 August 2019. Brilacidin (PMX-30063):...
    155 KB (14,566 words) - 15:16, 5 October 2024
  • ATC code J01 Antibacterials for systemic use is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric...
    14 KB (1,151 words) - 15:36, 25 January 2024