A plexin is a protein which acts as a receptor for semaphorin family signaling proteins. It is classically known for its expression on the surface of axon...
15 KB (1,611 words) - 18:10, 23 May 2024
Plexin-A1 is a protein that in humans is encoded by the PLXNA1 gene. Plexin A1 has been shown to interact with AKT1. GRCh38: Ensembl release 89: ENSG00000114554...
6 KB (703 words) - 22:19, 3 March 2023
in mice that have a Plexin-A3 defect. Specifically, axons that are connected to a transient target will retract once the Plexin-A3 receptors are activated...
23 KB (2,972 words) - 02:10, 7 June 2024
(Sema6D) expressed at the midline, which form a complex that signals to Nr-CAM/Plexin-A1 receptors on crossing RGC axons. Since all vertebrates, even the earliest...
15 KB (1,712 words) - 17:03, 3 July 2024
Plexin-A4 is a protein that in humans is encoded by the PLXNA4 gene. Plexin A4 binds to neuropilin 1 (Nrp1) and neuropilin 2 (Nrp2) and transduces signals...
6 KB (723 words) - 23:59, 3 March 2023
receptors are called plexins, with neuropilins as their co-receptors in many cases. The main receptors for semaphorins are plexins, which have established...
7 KB (870 words) - 07:16, 16 August 2023
induces growth cone collapse in the central nervous system. By binding plexin B1 receptor it functions as an R-Ras GTPase-activating protein (GAP) and...
10 KB (1,298 words) - 06:50, 24 December 2023
protein ORMDL sphingolipid biosynthesis regulator 3 PLXDC1: encoding protein Plexin domain-containing protein 1 PNPO: encoding enzyme Pyridoxine-5'-phosphate...
26 KB (1,899 words) - 01:58, 15 August 2024
Plexin-D1 is a protein that in humans is encoded by the PLXND1 gene. GRCh38: Ensembl release 89: ENSG00000004399 – Ensembl, May 2017 GRCm38: Ensembl release...
4 KB (453 words) - 23:20, 20 February 2024