In organic chemistry, polyketides are a class of natural products derived from a precursor molecule consisting of a chain of alternating ketone (>C=O...
21 KB (2,213 words) - 08:48, 26 May 2024
Polyketide synthases (PKSs) are a family of multi-domain enzymes or enzyme complexes that produce polyketides, a large class of secondary metabolites...
18 KB (2,138 words) - 16:43, 1 August 2024
Malonyl-CoA (section Polyketide biosynthesis)
It plays a key role in chain elongation in fatty acid biosynthesis and polyketide biosynthesis. Malonyl-CoA provides 2-carbon units to fatty acids and commits...
6 KB (574 words) - 09:54, 7 March 2024
class of aromatic polyketide antibiotics, also known as bacterial aromatic polyketides, produced by Streptomyces via type II polyketide synthases (PKSs)...
17 KB (1,684 words) - 15:43, 13 January 2024
Avermectin (category Polyketides)
of avermectin production: 1) production of the avermectin aglycon by polyketide synthases, 2) modification of the aglycon, 3) synthesis of modified sugars...
16 KB (1,799 words) - 22:49, 11 July 2024
Nonribosomal peptide (section Mixed with polyketides)
biosynthesis of nonribosomal peptides shares characteristics with the polyketide and fatty acid biosynthesis. Due to these structural and mechanistic similarities...
16 KB (1,833 words) - 15:06, 20 December 2023
polyketide are in RapC. Then, the linear polyketide is modified by the NRPS, RapP, which attaches L-pipecolate to the terminal end of the polyketide,...
69 KB (6,838 words) - 09:56, 30 July 2024
either from type ll polyketide or shikimate pathways. This claim was not disputed until a key intermediate exclusive to the polyketide pathway was isolated...
16 KB (1,506 words) - 00:07, 26 February 2024
of p-coumarate. Entering the flavone synthesis pathway, the type III polyketide synthase enzyme chalcone synthase (CHS) uses consecutive condensations...
11 KB (967 words) - 16:32, 27 May 2024
Aromatic polyketides are assembled by a type II (iterative) polyketide synthase in bacteria. Iterative type II polyketide syntheses produce polyketide chains...
3 KB (320 words) - 05:22, 4 April 2022