R-SMADs are receptor-regulated SMADs. SMADs are transcription factors that transduce extracellular TGF-β superfamily ligand signaling from cell membrane...
3 KB (304 words) - 23:23, 18 August 2023
sub-types of Smads: receptor-regulated Smads (R-Smads), common partner Smads (Co-Smads), and inhibitory Smads (I-Smads). The eight members of the Smad family...
35 KB (4,590 words) - 22:05, 24 August 2024
nanoparticles SMAD (protein), proteins involved in cell signaling I-SMAD, inhibitory SMAD proteins R-SMAD, receptor regulated SMAD proteins Smad, Syria, a...
454 bytes (88 words) - 09:31, 6 July 2021
TGF beta signaling pathway (section R-SMAD regulation)
receptor then phosphorylates receptor-regulated SMADs (R-SMADs) which can now bind the coSMAD SMAD4. R-SMAD/coSMAD complexes accumulate in the nucleus where...
20 KB (2,098 words) - 00:36, 28 November 2023
Paracrine signaling (section SMAD pathway)
phosphorylate SMAD proteins. There are three classes of SMADs: Receptor-regulated SMAD (R-SMAD) Common-mediator SMAD (Co-SMAD) Inhibitory SMAD (I-SMAD) Examples...
46 KB (4,967 words) - 21:12, 7 July 2024
regulation. SMAD 4 belongs to the co-SMAD group (common mediator SMAD), the second class of the SMAD family. SMAD4 is the only known co-SMAD in most metazoans...
28 KB (3,335 words) - 04:19, 25 July 2024
phosphorylation of R-Smads (Smad-1, Smad-5, Smad-8). Upon phosphorylation, formation of an R-SMAD complex in conjunction with common-partner Smad (co-Smad) occurs...
44 KB (5,478 words) - 21:37, 11 August 2024
Mothers against decapentaplegic homolog 3 (category R-SMAD)
3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene. SMAD3 is a member of the SMAD family of proteins...
33 KB (4,115 words) - 19:27, 8 July 2024
Mothers against decapentaplegic homolog 2 (redirect from SMAD family member 2)
also known as SMAD family member 2 or SMAD2, is a protein that in humans is encoded by the SMAD2 gene. MAD homolog 2 belongs to the SMAD, a family of proteins...
16 KB (1,925 words) - 23:04, 2 May 2024
a type I receptor. The type I receptor recruits a receptor regulated SMAD (R-SMAD) which it phosphorylates. The RSMAD then translocates to the nucleus...
6 KB (583 words) - 15:40, 29 March 2023