RNA Modification Base (RMBase) is designed for decoding the landscape of RNA modifications identified from high-throughput sequencing data (MeRIP-seq,...
3 KB (201 words) - 02:21, 29 May 2024
RNA editing (also RNA modification) is a molecular process through which some cells can make discrete changes to specific nucleotide sequences within an...
61 KB (7,435 words) - 14:08, 2 November 2024
2'-O-methylation (category RNA)
(2'-O-Me) is a common nucleotide epitranscriptomics modification of ribosomal RNA (rRNA). The rRNA is transcribed from DNA and then used to create proteins...
6 KB (703 words) - 00:13, 18 October 2024
nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and...
31 KB (3,892 words) - 08:04, 7 October 2024
Antisense RNA (asRNA), also referred to as antisense transcript, natural antisense transcript (NAT) or antisense oligonucleotide, is a single stranded RNA that...
24 KB (2,997 words) - 00:53, 25 July 2024
rRNAs and tRNAs are extensively modified, but snRNAs and mRNAs can also be the target of base modification. RNA can also be methylated. Like DNA, RNA can...
65 KB (7,617 words) - 15:36, 3 November 2024
Guide RNA (gRNA) or single guide RNA (sgRNA) is a short sequence of RNA that functions as a guide for the Cas9-endonuclease or other Cas-proteins that...
30 KB (3,643 words) - 08:03, 2 November 2024
susceptible to this base-catalyzed hydrolysis because the ribose sugar in RNA has a hydroxyl group at the 2’ position. This feature makes RNA chemically unstable...
6 KB (740 words) - 02:24, 6 August 2024
Transfer RNA (abbreviated tRNA and formerly referred to as sRNA, for soluble RNA) is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides...
67 KB (8,008 words) - 03:06, 6 November 2024
Epitranscriptome (category RNA)
ribosomal RNA (rRNA), transfer RNA (tRNA), messenger RNA (mRNA), and small nuclear RNA (snRNA). The most common and well-understood mRNA modification at present...
61 KB (7,732 words) - 20:34, 13 May 2024