Ryanodine receptor 1 (redirect from RyR1)
found primarily in skeletal muscle. In humans, it is encoded by the RYR1 gene. RYR1 functions as a calcium release channel in the sarcoplasmic reticulum...
11 KB (1,344 words) - 04:45, 10 March 2024
to at least six genetic mutations, with the most common one being of the RYR1 gene. These genetic variations are often inherited in an autosomal dominant...
45 KB (4,933 words) - 15:34, 26 July 2024
high affinity to them. There are multiple isoforms of ryanodine receptors: RyR1 is primarily expressed in skeletal muscle RyR2 is primarily expressed in...
21 KB (2,355 words) - 13:40, 24 June 2024
Most cases have demonstrable mutations in the ryanodine receptor type 1 (RYR1) gene, which are often de novo (newly developed). People with CCD are at...
6 KB (479 words) - 15:22, 21 June 2024
thermogenesis enhances the life-threatening response to heat in mice with an Ryr1 mutation". Nature Communications. 11 (1): 5099. Bibcode:2020NatCo..11.5099W...
4 KB (389 words) - 17:14, 17 May 2024
Hadrurus gertschi. Hadrucalcin modifies the Ryanodine receptor channels RyR1 and RyR2, found in the sarcoplasmic reticulum, to a long-lasting subconductance...
6 KB (609 words) - 04:32, 27 January 2024
direct coupling between the sarcoplasmic reticulum calcium release channel RYR1 (ryanodine receptor 1), and voltage-gated L-type calcium channels (identified...
120 KB (13,834 words) - 11:46, 13 June 2024
antagonist and a voltage-independent activator of the ryanodine receptors (RYR1, RYR2, and RYR3). It is also a competitive antagonist of the ionotropic glycine...
200 KB (19,951 words) - 05:44, 12 August 2024
(RyR1) is expressed in skeletal muscles in mammals. The alterations in the calcium potentials which are caused by intrepicalcin interaction with RyR1,...
9 KB (1,129 words) - 18:50, 30 April 2024
thermogenesis enhances the life-threatening response to heat in mice with an Ryr1 mutation". Nature Communications. 11 (1): 5099. Bibcode:2020NatCo..11.5099W...
29 KB (3,186 words) - 07:18, 25 July 2024