• Thumbnail for Lentiviral vector in gene therapy
    Lentiviral vectors in gene therapy is a method by which genes can be inserted, modified, or deleted in organisms using lentiviruses. Lentiviruses are a...
    29 KB (3,429 words) - 16:34, 22 October 2024
  • Gene therapy using lentiviral vectors was being explored in early stage trials as of 2009.[needs update] In a Phase I clinical trial of three patients...
    11 KB (1,503 words) - 11:37, 18 July 2024
  • Thumbnail for Gene therapy
    a lentiviral vector administered in a US human clinical trial. In May 2007, researchers announced the first gene therapy trial for inherited retinal disease...
    176 KB (18,162 words) - 07:40, 2 November 2024
  • Thumbnail for CRISPR gene editing
    patients using CRISPR-Cas9 technology have shown promising results. Nevertheless, there remains a few limitations of the technology's use in gene therapy: the...
    170 KB (19,893 words) - 05:47, 2 November 2024
  • Fondation pour la Recherche Médicale Retinal gene therapy using lentiviral vectors Viral vector Lentiviral vector in gene therapy Chimeric antigen receptor Charneau...
    9 KB (860 words) - 03:58, 8 June 2024
  • Thumbnail for Induced pluripotent stem cell
    cMyc, using a retroviral system, while Thomson and colleagues used a different set of factors, Oct4, Sox2, Nanog, and Lin28, using a lentiviral system...
    92 KB (10,512 words) - 19:18, 10 October 2024
  • Thumbnail for Sickle cell disease
    reportedly had been successfully treated in mice using gene therapy. The researchers used a viral vector to make the mice—which have essentially the same...
    140 KB (15,033 words) - 22:13, 2 November 2024
  • Stargardt disease (category Pages using the JsonConfig extension)
    Stargardt disease is the most common inherited single-gene retinal disease. In terms of the first description of the disease, it follows an autosomal recessive...
    24 KB (2,922 words) - 10:54, 28 August 2024
  • Thumbnail for Intracellular delivery
    Intracellular delivery (category Gene delivery)
    of the IVF and ICSI procedure. HSC-based gene therapies prepared with gamma retroviral and lentiviral vectors have in some cases shown an increased risk...
    78 KB (8,788 words) - 19:06, 6 August 2024