Mothers against decapentaplegic homolog 6 (redirect from SMAD6)
SMAD family member 6, also known as SMAD6, is a protein that in humans is encoded by the SMAD6 gene. SMAD6 is a protein that, as its name describes, is...
11 KB (1,283 words) - 06:30, 11 December 2023
other SMADs which complete the SMAD family, the inhibitory SMADs (I-SMADS), SMAD6 and SMAD7. They play a key role in the regulation of TGF beta signaling...
20 KB (2,098 words) - 14:36, 28 September 2024
modulation of transforming growth factor beta ligands. This class includes SMAD6 and SMAD7. They compete with SMAD4 and consequently regulate the transcription...
763 bytes (63 words) - 07:35, 28 March 2022
Class SMADs R-SMAD SMAD1, SMAD2, SMAD3, SMAD5 and SMAD8/9 Co-SMAD SMAD4 I-SMAD SMAD6 and SMAD7...
46 KB (4,967 words) - 21:12, 7 July 2024
triggers apoptosis. The SMAD pathway is regulated by feedback inhibition. SMAD6 and SMAD7 may block type I receptors. There is also substantial evidence...
70 KB (8,486 words) - 02:10, 19 August 2024
Finally, Smad6 and Smad7 are I-Smads that work to suppress the activity of R-Smads. While Smad7 is a general TGF-B signal inhibitor, Smad6 associates...
35 KB (4,590 words) - 22:05, 24 August 2024
activated in response to BMPs bone morphogenetic protein or GDP signals. SMAD6 and SMAD7 may be referred to as I-SMADs (inhibitory SMADS), which form trimers...
3 KB (304 words) - 23:23, 18 August 2023
closure, microcephaly; usually considered nonsyndromic. Craniosynostosis (SMAD6) Usually considered nonsyndromic. Craniosynostosis (TWIST1) Coronal (right...
52 KB (2,779 words) - 23:07, 7 October 2024
enhancer-binding factor (TCF/LEF), GATA2/3, retinoic acid receptor α, and SMAD6/7 don't affect the expression of C/EBPβ and C/EBPδ but inhibit the induction...
24 KB (2,438 words) - 11:40, 21 February 2024
P84022 15274 SMAD4 HGNC:6770 Q13485 15275 SMAD5 HGNC:6771 Q99717 15276 SMAD6 HGNC:6772 O43541 15277 SMAD7 HGNC:6773 O15105 15278 SMAD9 HGNC:6774 O15198...
242 KB (17 words) - 18:43, 6 October 2024