Semaphorins are a class of secreted and membrane proteins that were originally identified as axonal growth cone guidance molecules. They primarily act...
7 KB (870 words) - 07:16, 16 August 2023
Semaphorin-3A is a protein that in humans is encoded by the SEMA3A gene. The SEMA3A gene is a member of the semaphorin family and encodes a protein with...
14 KB (1,729 words) - 23:05, 27 March 2024
Semaphorin 3E is a protein that in humans is encoded by the SEMA3E gene. Semaphorin are a large family of conserved secreted and membrane associated proteins...
4 KB (618 words) - 07:59, 3 December 2023
SEMA4D (redirect from Semaphorin 4D)
Semaphorin-4D (SEMA4D) also known as Cluster of Differentiation 100 (CD100), is a protein of the semaphorin family that in humans is encoded by the SEMA4D...
10 KB (1,298 words) - 06:50, 24 December 2023
A plexin is a protein which acts as a receptor for semaphorin family signaling proteins. It is classically known for its expression on the surface of axon...
15 KB (1,611 words) - 18:10, 23 May 2024
attraction of apical dendrites of pyramidal cells in cortical layer V towards semaphorin-3A (Sema3a). Whereas the axons of pyramidal cells are repelled by Sema3a...
11 KB (1,122 words) - 01:24, 20 February 2024
Semaphorin-5A is a protein that in humans is encoded by the SEMA5A gene. Members of the semaphorin protein family, such as SEMA5A, are involved in axonal...
7 KB (587 words) - 10:20, 17 October 2022
repulsion, and also initiate pruning of exuberant synaptic connections. Semaphorin ligands and the receptors neuropilins and plexins are used to induce retraction...
23 KB (2,972 words) - 02:10, 7 June 2024
is linked to Semaphorin 6A, which is an inhibitor of angiogenesis. Overexpression of miR-27b decreased the protein expression of Semaphorin 6A which favored...
4 KB (415 words) - 04:07, 22 January 2021
of numerous trophic and tropic factors; netrins, slits, ephrins and semaphorins are four well-studied tropic cues (Fig.1). The growth cone is capable...
26 KB (3,128 words) - 08:14, 18 August 2023