Semaphorins are a class of secreted and membrane proteins that were originally identified as axonal growth cone guidance molecules. They primarily act...

Semaphorin-3A is a protein that in humans is encoded by the SEMA3A gene. The SEMA3A gene is a member of the semaphorin family and encodes a protein with...

Semaphorin 3E is a protein that in humans is encoded by the SEMA3E gene. Semaphorin are a large family of conserved secreted and membrane associated proteins...

Semaphorin-4D (SEMA4D) also known as Cluster of Differentiation 100 (CD100), is a protein of the semaphorin family that in humans is encoded by the SEMA4D...

A plexin is a protein which acts as a receptor for semaphorin family signaling proteins. It is classically known for its expression on the surface of axon...

attraction of apical dendrites of pyramidal cells in cortical layer V towards semaphorin-3A (Sema3a). Whereas the axons of pyramidal cells are repelled by Sema3a...

Semaphorin-5A is a protein that in humans is encoded by the SEMA5A gene. Members of the semaphorin protein family, such as SEMA5A, are involved in axonal...

repulsion, and also initiate pruning of exuberant synaptic connections. Semaphorin ligands and the receptors neuropilins and plexins are used to induce retraction...

is linked to Semaphorin 6A, which is an inhibitor of angiogenesis. Overexpression of miR-27b decreased the protein expression of Semaphorin 6A which favored...

of numerous trophic and tropic factors; netrins, slits, ephrins and semaphorins are four well-studied tropic cues (Fig.1). The growth cone is capable...