Sequencing by ligation is a DNA sequencing method that uses the enzyme DNA ligase to identify the nucleotide present at a given position in a DNA sequence...

structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encoding". Genome Research. 19 (9):...

SOLiD (Sequencing by Oligonucleotide Ligation and Detection) is a next-generation DNA sequencing technology developed by Life Technologies and has been...

end-to-end distance to detect the successive ligation of oligonucleotide. First step of sequencing by ligation is using a primer to extend a DNA fragment...

lengths comparable to Illumina sequencing. This sequencing by ligation method has been reported to have some issue sequencing palindromic sequences. Ion Torrent...

created by DNA ligation. Another way, barcode-targeted sequencing, DNA circularization of a padlock probe with a barcode sequence is conducted by ligation only...

of probes that call-out a single base with each hybridization) Sequencing by ligation Drmanac, Radoje; Drmanac, Snezana; Chui, Gloria; Diaz, Robert; Hou...

released early 2018. SOLiD systems was acquired by Applied Biosystems in 2006. SOLiD applies sequencing by ligation and dual base encoding. The first SOLiD system...

breaks and must be repaired before biotin pulldown and sequencing adaptor ligation. This is achieved by using a combination of enzymes that fill in 5’ overhangs...

cells is used in sequencing the DNA or RNA using traditional methods like Sanger sequencing or next generation sequencing. By deep sequencing of DNA and RNA...