VEGF receptors (VEGFRs) are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending...

act as VEGF receptors. In mammals, the VEGF family comprises five members: VEGF-A, placenta growth factor (PGF), VEGF-B, VEGF-C and VEGF-D. The latter...

class II (Insulin receptor family) RTK class III (PDGF receptor family) RTK class IV (VEGF receptors family) RTK class V (FGF receptor family) RTK class...

domain receptor (KDR, a type IV receptor tyrosine kinase) also known as vascular endothelial growth factor receptor 2 (VEGFR-2) is a VEGF receptor. KDR...

factor receptor 1 is a protein that in humans is encoded by the FLT1 gene. FLT1 is a member of VEGF receptor gene family. It encodes a receptor tyrosine...

stimulated by VEGF: sunitinib, sorafenib, axitinib, and pazopanib (some of these therapies target VEGF receptors rather than the VEGFs). Both antibody-based...

of VEGF-C is to promote the growth of lymphatic vessels (lymphangiogenesis). It acts on lymphatic endothelial cells (LECs) primarily via its receptor VEGFR-3...

characterized. VEGF-A shows prominent activity with vascular endothelial cells, primarily through its interactions with the VEGFR1 and -R2 receptors found prominently...

non-membrane associated splice variant of VEGF receptor 1 (Flt-1), sFlt-1 binds the angiogenic factors VEGF (vascular endothelial growth factor) and PlGF...

sclerosis. VEGF-B exerts its effects via the FLT1 receptor. But the role of co-receptor NRP in VEGF-B-mediated effects is still unclear. VEGF-B has also...