VEGF receptors (VEGFRs) are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending...
8 KB (755 words) - 18:51, 2 November 2023
Vascular endothelial growth factor (redirect from VEGF)
act as VEGF receptors. In mammals, the VEGF family comprises five members: VEGF-A, placenta growth factor (PGF), VEGF-B, VEGF-C and VEGF-D. The latter...
40 KB (4,580 words) - 05:24, 3 June 2024
class II (Insulin receptor family) RTK class III (PDGF receptor family) RTK class IV (VEGF receptors family) RTK class V (FGF receptor family) RTK class...
28 KB (3,078 words) - 07:46, 3 June 2024
domain receptor (KDR, a type IV receptor tyrosine kinase) also known as vascular endothelial growth factor receptor 2 (VEGFR-2) is a VEGF receptor. KDR...
6 KB (794 words) - 11:50, 18 May 2022
VEGFR1 (category Tyrosine kinase receptors)
factor receptor 1 is a protein that in humans is encoded by the FLT1 gene. FLT1 is a member of VEGF receptor gene family. It encodes a receptor tyrosine...
9 KB (1,086 words) - 00:25, 5 October 2022
stimulated by VEGF: sunitinib, sorafenib, axitinib, and pazopanib (some of these therapies target VEGF receptors rather than the VEGFs). Both antibody-based...
14 KB (1,671 words) - 06:48, 24 August 2024
Vascular endothelial growth factor C (redirect from VEGF-C)
of VEGF-C is to promote the growth of lymphatic vessels (lymphangiogenesis). It acts on lymphatic endothelial cells (LECs) primarily via its receptor VEGFR-3...
27 KB (3,104 words) - 23:27, 27 March 2024
Vascular endothelial growth factor A (redirect from VEGF-A)
characterized. VEGF-A shows prominent activity with vascular endothelial cells, primarily through its interactions with the VEGFR1 and -R2 receptors found prominently...
24 KB (3,053 words) - 21:43, 17 August 2024
non-membrane associated splice variant of VEGF receptor 1 (Flt-1), sFlt-1 binds the angiogenic factors VEGF (vascular endothelial growth factor) and PlGF...
19 KB (2,341 words) - 00:54, 8 November 2023
Vascular endothelial growth factor B (redirect from VEGF-B)
sclerosis. VEGF-B exerts its effects via the FLT1 receptor. But the role of co-receptor NRP in VEGF-B-mediated effects is still unclear. VEGF-B has also...
14 KB (1,558 words) - 02:03, 27 November 2023