Vpu is an accessory protein that in HIV is encoded by the vpu gene. Vpu stands for "Viral Protein U". The Vpu protein acts in the degradation of CD4 in...

vision tasks Viral protein U (Vpu), a regulatory protein found in HIV-1 Vancouver Police Union, a trade union in Canada Search for "vpu" on Wikipedia. All...

target for ERAD. However, HIV produces the membrane protein Vpu that binds to CD4. The Vpu protein mainly retains the CD4 in the ER by SCFβ-TrCP-dependent...

vpu (Virus protein U) – Vpu is specific to HIV-1. It is a class I oligomeric integral membrane phosphoprotein with numerous biological functions. Vpu...

class I and class II molecules. Nef also interacts with SH3 domains. The vpu protein (p16) influences the release of new virus particles from infected cells...

(November 2001). "The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor kappaB-dependent...

SIVs use the Nef protein to remove tetherin from the cell membrane whereas HIV-1 uses the Vpu protein degrade the defence protein. Tetherin is a conserved...

(1996). "The human immunodeficiency virus type 1 Vpu protein: a potential regulator of proteolysis and protein transport in the mammalian secretory pathway"...

JS (April 2010). "Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps". PLOS Pathogens...

non-structural proteins, named Viral Protein U (Vpu) and Viral Protein R (Vpr), part of a new class of retroviral proteins – designated accessory proteins – that...