inhibitor 1B (p27Kip1) is an enzyme inhibitor that in humans is encoded by the CDKN1B gene. It encodes a protein which belongs to the Cip/Kip family of cyclin...

P27 may refer to: CDKN1B, cyclin-dependent kinase inhibitor 1B ČZ vz. 27, a pistol IFI27, interferon alpha-inducible protein 27 Papyrus 27, a biblical...

a fourth form of multiple endocrine neoplasia ("MEN4"), associated with CDKN1B. The presentation is believed to overlap that of MEN1 and MEN2. The MEN1...

trastuzumab activates is the tumor suppressor p27 (kip1), also known as CDKN1B. Trastuzumab has been shown to inhibit HER2/neu ectodomain cleavage in breast...

binding affinity. Known CDK inhibitors are p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Drugs that inhibit Cdk2 and arrest the cell cycle, such as GW8510 and...

and prevent or reverse hearing loss. The cell cycle inhibitor p27kip1 (CDKN1B) has also been found to encourage regrowth of cochlear hair cells in mice...

disease. The tumors often harbour loss of chromosome 18q. Mutations in CDKN1B are present in approximately 8% of cases. The treatment traditionally consists...

Cyclin-dependent kinase 6 p21 / WAF1 CDKN1A Cyclin E1/Cyclin-dependent kinase 2 p27 CDKN1B Cyclin D3/Cyclin-dependent kinase 4, Cyclin E1/Cyclin-dependent kinase 2...

endocrine neoplasia can be brought on by mutations in the MEN1, RET, and CDKN1B genes. Addison's disease, or primary adrenal insufficiency, is an uncommon...

and transcribe Cyclin A and Cdc 6. Cyclin-dependent kinase inhibitor 1B (CDKN1B), also known as p27, binds to and prevents the activation of CyclinE:Cdk2...