Clozapine is a psychiatric medication and was the first atypical antipsychotic (also called second-generation antipsychotic) to be discovered. It is primarily...
120 KB (12,555 words) - 12:31, 5 August 2024
antipsychotics, known as atypical antipsychotics, arrived with the introduction of clozapine in the early 1970s followed by others (e.g., risperidone). Both generations...
208 KB (18,297 words) - 10:03, 18 August 2024
Clozapine N-oxide (CNO) is a synthetic drug used mainly in biomedical research as a ligand to activate DREADD receptors. Although CNO was initially believed...
5 KB (463 words) - 07:20, 18 January 2024
risperidone and olanzapine; and produce weight gain similar to risperidone, clozapine and aripiprazole. They concluded that it produces suicide attempt, suicide;...
79 KB (6,533 words) - 11:42, 20 June 2024
member of the dibenzoxazepine class and structurally very similar to clozapine. Several researchers have argued that loxapine, initially classified as...
16 KB (1,076 words) - 12:36, 5 August 2024
a major active metabolite of the atypical antipsychotic drug clozapine. Unlike clozapine, it possesses intrinsic activity at the D2/D3 receptors, and...
6 KB (524 words) - 23:54, 28 October 2023
DHA-clozapine (tentative trade name Clozaprexin) is an atypical antipsychotic drug candidate that was created and originally tested by chemists at Protarga...
4 KB (151 words) - 02:21, 22 August 2024
cases of bowel obstruction or constipation (such as those related to clozapine treatment) fecal vomiting has been identified as a cause of death. Fecal...
4 KB (338 words) - 04:47, 14 March 2024
quit before the 6-week completion date. Treatment with olanzapine (like clozapine) may result in increased weight gain and increased glucose and cholesterol...
92 KB (8,663 words) - 12:39, 5 August 2024
meta-analysis of 15 antipsychotic drugs, clozapine was significantly more effective than all other drugs, although clozapine's heavily multimodal action may cause...
170 KB (18,637 words) - 11:33, 22 August 2024