B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription of DNA, cytokine production and cell survival. NF-κB...
89 KB (9,773 words) - 14:28, 22 August 2024
Look up NF or nf in Wiktionary, the free dictionary. NF may refer to: NF (rapper), American hip hop musician NF (EP), 2014 Neurofibromatosis, a medical...
2 KB (269 words) - 18:54, 8 August 2024
activation of the canonical NF-κB pathway by TNFR1. Thus, TNFR2 non-canonical NF-κB activation is dependent on the canonical NF-κB activation by TNFR1, as...
68 KB (8,794 words) - 22:31, 1 September 2024
lymphocytes. The IκB kinase enzyme complex is part of the upstream NF-κB signal transduction cascade. The IκBα (inhibitor of nuclear factor kappa B) protein inactivates...
14 KB (1,447 words) - 09:31, 22 December 2023
T-cell receptor (section NF-κB)
degradation of I-κB. I-κB blocks the NLS of NF-κB therefore preventing its translocation to the nucleus. Once I-κB is degraded, it cannot bind to NF-κB and the...
43 KB (5,372 words) - 15:31, 6 August 2024
CHUK (section NF-κB response)
by the CHUK gene. IKK-α is part of the IκB kinase complex that plays an important role in regulating the NF-κB transcription factor. However, IKK-α has...
23 KB (2,765 words) - 20:13, 7 July 2024
a REL-associated protein involved in NF-κB heterodimer formation, nuclear translocation and activation. NF-κB is an essential transcription factor complex...
56 KB (6,507 words) - 07:54, 19 July 2024
protein that cleaves A20, an inhibitory protein of NF-κB signaling (which acts by deubiquitylating NF-κB's ubiquitylation substrates, having an inhibitory...
18 KB (2,173 words) - 16:05, 30 November 2023
exhibit pathologically overactive NF-κB, PI3K/AKT/mTOR, JAK-STAT0, MAPK/ERK, B-cell receptor, toll-like receptor, and NF-κB signaling pathways and thereby...
69 KB (8,143 words) - 18:36, 22 January 2024
derivatives are synthesized by regio/stereoselective Michael addition to ring A. NF-κB is a transcription factor that regulates many genes involved in cell survival...
9 KB (764 words) - 13:54, 5 March 2024