• Look up braf in Wiktionary, the free dictionary. BRAF may refer to: Baton Rouge Area Foundation BRAF (gene) This disambiguation page lists articles associated...
    134 bytes (49 words) - 19:58, 23 April 2024
  • Thumbnail for BRAF (gene)
    BRAF is a human gene that encodes a protein called B-Raf. The gene is also referred to as proto-oncogene B-Raf and v-Raf murine sarcoma viral oncogene...
    49 KB (5,285 words) - 12:09, 26 July 2024
  • V600E (redirect from BRAF V600)
    V600E is a mutation of the BRAF gene in which valine (V) is substituted by glutamic acid (E) at amino acid 600. It is a driver mutation in a proportion...
    8 KB (728 words) - 02:23, 29 November 2023
  • Thumbnail for Trametinib
    within 6 to 7 months. To overcome this, trametinib was combined with the BRAF inhibitor dabrafenib. As a result of this research, on 8 January 2014, the...
    15 KB (975 words) - 03:53, 27 June 2024
  • Thumbnail for Melanoma
    subtypes: BRAF mutant, RAS mutant, NF1 mutant, and triple wild-type. The most frequent mutation occurs in the 600th codon of BRAF (50% of cases). BRAF is normally...
    154 KB (16,076 words) - 04:50, 7 August 2024
  • Thumbnail for Dabrafenib
    for the treatment of cancers associated with a mutated version of the gene BRAF. Dabrafenib acts as an inhibitor of the associated enzyme B-Raf, which plays...
    16 KB (1,122 words) - 03:21, 24 April 2024
  • Thumbnail for Erdheim–Chester disease
    approved in 2019, targets the BRAF protein. It was approved after showing dramatic efficacy in ECD patients harboring the BRAF V600E mutation. Cobimetinib...
    22 KB (2,228 words) - 20:53, 6 January 2024
  • Thumbnail for Tovorafenib
    relapsed or refractory pediatric low-grade glioma harboring a BRAF fusion or rearrangement, or BRAF V600 mutation. Efficacy was evaluated in 76 participants...
    9 KB (516 words) - 03:00, 14 May 2024
  • Thumbnail for BANCR
    BRAF-activated non-protein coding RNA is a noncoding RNA that in humans is encoded by the BANCR gene. Long non-coding RNAs (lncRNAs) are involved in the...
    5 KB (675 words) - 15:00, 15 March 2024
  • (GSK1120212), FDA-approved to treat BRAF-mutated melanoma. Also studied in combination with BRAF inhibitor dabrafenib to treat BRAF-mutated melanoma. PD-325901...
    6 KB (719 words) - 23:12, 12 May 2024