Look up braf in Wiktionary, the free dictionary. BRAF may refer to: Baton Rouge Area Foundation BRAF (gene) This disambiguation page lists articles associated...
134 bytes (49 words) - 19:58, 23 April 2024
BRAF is a human gene that encodes a protein called B-Raf. The gene is also referred to as proto-oncogene B-Raf and v-Raf murine sarcoma viral oncogene...
49 KB (5,285 words) - 12:09, 26 July 2024
within 6 to 7 months. To overcome this, trametinib was combined with the BRAF inhibitor dabrafenib. As a result of this research, on 8 January 2014, the...
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Melanoma (section BRAF inhibitors)
subtypes: BRAF mutant, RAS mutant, NF1 mutant, and triple wild-type. The most frequent mutation occurs in the 600th codon of BRAF (50% of cases). BRAF is normally...
154 KB (16,076 words) - 04:50, 7 August 2024
for the treatment of cancers associated with a mutated version of the gene BRAF. Dabrafenib acts as an inhibitor of the associated enzyme B-Raf, which plays...
16 KB (1,122 words) - 03:21, 24 April 2024
approved in 2019, targets the BRAF protein. It was approved after showing dramatic efficacy in ECD patients harboring the BRAF V600E mutation. Cobimetinib...
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relapsed or refractory pediatric low-grade glioma harboring a BRAF fusion or rearrangement, or BRAF V600 mutation. Efficacy was evaluated in 76 participants...
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BANCR (redirect from Braf-activated non-protein coding rna)
BRAF-activated non-protein coding RNA is a noncoding RNA that in humans is encoded by the BANCR gene. Long non-coding RNAs (lncRNAs) are involved in the...
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(GSK1120212), FDA-approved to treat BRAF-mutated melanoma. Also studied in combination with BRAF inhibitor dabrafenib to treat BRAF-mutated melanoma. PD-325901...
6 KB (719 words) - 23:12, 12 May 2024