ADME is the four-letter abbreviation (acronym) for absorption, distribution, metabolism, and excretion, and is mainly used in fields such as pharmacokinetics...
7 KB (817 words) - 21:13, 17 May 2024
Stevens–Johnson syndrome (section ADME)
distribute to tissues, metabolize, or excrete (this combination is termed ADME) a drug are predisposed to develop SJS.[citation needed] Although SJS can...
56 KB (5,844 words) - 03:24, 2 September 2024
saw the introduction of the new resource ADME SARfari - a tool for predicting and comparing cross-species ADME targets. ChEMBL: Quick Tour on EBI Train...
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Pharmacokinetics (section ADME)
enters into contact with the organism, these are described using the acronym ADME (or LADME if liberation is included as a separate step from absorption):...
46 KB (4,510 words) - 13:42, 23 September 2024
fulfillment of the ADME criteria. To be an effective drug, a compound not only must be active against a target, but also possess the appropriate ADME (Absorption...
5 KB (604 words) - 02:36, 28 June 2024
pharmacokinetics discusses the absorption, distribution, metabolism, and excretion (ADME) of chemicals from the biological systems. Pharmacology is not synonymous...
48 KB (4,744 words) - 21:42, 24 September 2024
involved in the development of specific drug-induced SCARs. Variations in ADME, i.e. an individual's efficiency in absorbing, distributing, metabolizing...
38 KB (4,291 words) - 18:22, 3 September 2024
improve how the drug is absorbed, distributed, metabolized, and excreted (ADME). Prodrugs are often designed to improve bioavailability when a drug itself...
12 KB (1,281 words) - 06:14, 9 September 2024
Tetramethylammonium (TMA) is the simplest quaternary ammonium cation. It has the chemical formula [Me4N]+ and consists of four methyl groups (−CH3, denoted...
17 KB (1,706 words) - 19:26, 15 September 2024
voiced environments (e.g. hazte /ˈaΘte/, → [ˈaθte], vs hazme /ˈaΘme/, → [ˈaðme]; or las manos /laS ˈmanoS/, → [lazˈmanos]). ⟨V⟩, ⟨F⟩ and ⟨C⟩ have completely...
164 KB (15,919 words) - 14:38, 30 September 2024