• Thumbnail for ATG16L1
    Autophagy related 16 like 1 is a protein that in humans is encoded by the ATG16L1 gene. This protein is characterized as a subunit of the autophagy-related...
    16 KB (1,731 words) - 06:41, 27 September 2024
  • ATG12-ATG5 protein-protein conjugate combines with additional proteins such as ATG16L1 or TECPR1 to form E3 ligases that spatially guide the formation of protein-lipid...
    16 KB (1,693 words) - 14:23, 4 September 2024
  • Thumbnail for Autophagy
    phosphoinositides) protein family, was recently shown to physically bind ATG16L1. Atg16L1 is a member of an E3-like protein complex involved in one of two ubiquitin-like...
    77 KB (9,112 words) - 23:14, 20 September 2024
  • Thumbnail for Crohn's disease
    pathogen-recognition receptor, NOD2; the autophagy-related 16-like 1, ATG16L1 and the immunity-related GTPase M, IRGM) are involved in innate immune...
    163 KB (18,582 words) - 06:39, 3 October 2024
  • Thumbnail for MTOR
    ULK1 and principal components (Beclin 1 and ATG16L1) of other complexes (Beclin 1-VPS34-ATG14 and ATG16L1-ATG5-ATG12) initiating autophagy, many of them...
    119 KB (12,658 words) - 19:25, 19 September 2024
  • Thumbnail for Buruli ulcer
    linked to variants in six immunity-related genes: SLC11A1, PRKN, NOD2, ATG16L1, iNOS, and IFNG, as well as in two long non-coding RNAs. A genome-wide...
    44 KB (5,126 words) - 02:57, 28 January 2024
  • Thumbnail for Inflammatory bowel disease
    in IBD by activating the non-classical autophagy pathway, dependent on Atg16L1 and NOD2 genes. B. thetaiotaomicron induces the differentiation of T regulatory...
    102 KB (11,217 words) - 02:20, 11 October 2024
  • O94817 1205 ATG13 HGNC:29091 O75143 1206 ATG14 HGNC:19962 Q6ZNE5 1207 ATG16L1 HGNC:21498 Q676U5 1208 ATG16L2 HGNC:25464 Q8NAA4 1209 ATG101 HGNC:25679...
    277 KB (17 words) - 18:34, 6 October 2024
  • Thumbnail for Autophagy protein 5
    autophagic vesicles. It is activated by ATG7 and forms a complex with ATG12 and ATG16L1. This complex is necessary for LC3-I (microtubule-associated proteins 1A/1B...
    22 KB (2,808 words) - 09:48, 15 April 2024
  • Thumbnail for Autophagosome
    After the formation of the spherical structure, the complex of ATG12-ATG5:ATG16L1 dissociates from the autophagosome. LC3 is cleaved by ATG4 protease to...
    7 KB (873 words) - 04:56, 19 July 2024