Integrin alpha L (redirect from Antigens, cd11a)
Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a protein that in humans...
10 KB (1,239 words) - 08:31, 10 June 2024
endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by rhinovirus as a receptor...
19 KB (2,409 words) - 16:20, 11 December 2023
determined for the I-domains of integrins CD11b (with bound magnesium) and CD11a (with bound manganese). The domain adopts a classic alpha/beta Rossmann...
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component is CD18 (β2) and mediate leukocyte adhesion. For example, LFA1 (CD11a/CD18) short representation of Lymphocyte Function-associated Antigen 1,...
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administered once weekly by subcutaneous injection. Efalizumab binds to the CD11a subunit of lymphocyte function-associated antigen 1 and acts as an immunosuppressant...
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located on the αM chain (CD11b) and HNA-5 is located on the αL integrin unit (CD11a). Two functionally unequal subpopulations of neutrophils were identified...
54 KB (5,770 words) - 22:58, 3 November 2024
Adhesion between FDCs and B cells is mediated by ICAM-1 (CD54)–LFA-1 (CD11a) and VCAM–VLA-4 molecules. Activated B-cells with low affinity to antigen...
16 KB (1,896 words) - 15:59, 6 April 2024
Otelixizumab Teplizumab Visilizumab CD4 Clenoliximab Keliximab Zanolimumab CD11a Efalizumab CD18 Erlizumab CD20 Obinutuzumab Ocrelizumab (+hyaluronidase)...
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integrins. The known binding partners of CD18 are CD11a, CD11b, CD11c and CD11d. Binding of CD18 and CD11a results in the formation of lymphocyte function-associated...
11 KB (1,299 words) - 10:15, 11 December 2023
alefacept. Efalizumab is a monoclonal antibody that specifically targets the CD11a subunit of LFA-1. It also blocks the adhesion molecules on the endothelial...
116 KB (13,061 words) - 15:20, 6 November 2024