Drosha is a Class 2 ribonuclease III enzyme that in humans is encoded by the DROSHA (formerly RNASEN) gene. It is the primary nuclease that executes the...
17 KB (1,975 words) - 03:44, 16 September 2024
romanized: sakartvelos sakhelmts'ipo drosha), also known as the Five-Cross Flag (ხუთჯვრიანი დროშა, khutjvriani drosha), is one of the national symbols of...
16 KB (1,396 words) - 02:04, 28 September 2024
enzyme Drosha, a protein that cuts RNA, to form the Microprocessor complex. In this complex, DGCR8 orients the catalytic RNase III domain of Drosha to liberate...
148 KB (16,818 words) - 04:03, 13 October 2024
animal cells. The complex is minimally composed of the ribonuclease enzyme Drosha and the dimeric RNA-binding protein DGCR8 (also known as Pasha in non-human...
18 KB (1,935 words) - 07:02, 6 May 2024
melanogaster and Caenorhabditis elegans, the protein is known as Pasha (partner of Drosha). It is a required component of the RNA interference pathway. The subunit...
6 KB (744 words) - 12:45, 5 April 2024
suppression of the organism. Class 3 RNase III Class 3 RNases III include the Drosha family of enzymes known to function in maturation of precursors to microRNA...
12 KB (1,386 words) - 19:11, 24 July 2024
and Drosha proteins. However some microRNAs, mirtrons, are known to be derived from introns via a different pathway which bypasses Pasha and Drosha. Some...
5 KB (626 words) - 19:34, 28 August 2023
proteins Drosha and Pasha, which are critical to canonical microRNA biogenesis. It is the only animal thus far reported to be missing Drosha. MicroRNAs...
19 KB (2,174 words) - 06:25, 4 May 2024
family, like DROSHA, play a role in processing precursor rRNAs, contributing to the assembly of functional ribosomes. DICER and DROSHA also from the...
25 KB (2,688 words) - 14:55, 15 October 2024
stem-loop structures known as pre-miRNA in the cell nucleus by the enzymes Drosha and Pasha. After being exported, it is then processed to mature miRNAs in...
102 KB (11,438 words) - 16:50, 17 July 2024