• Thumbnail for Flap structure-specific endonuclease 1
    function of this protein, leading to site-specific trinucleotide expansions. Flap structure-specific endonuclease 1 has been shown to interact with: APEX1...
    23 KB (2,642 words) - 21:34, 20 February 2024
  • Flap endonucleases (FENs, also known as 5' durgs in older references) are a class of nucleolytic enzymes that act as both 5'-3' exonucleases and structure-specific...
    5 KB (614 words) - 03:57, 20 February 2024
  • typically called restriction endonucleases or restriction enzymes, cleave only at very specific nucleotide sequences. Endonucleases differ from exonucleases...
    25 KB (2,688 words) - 14:55, 15 October 2024
  • Thumbnail for Primer (molecular biology)
    creating a short flap that is directly removed by flap structure-specific endonuclease 1 (FEN-1), which cleaves the 5’ overhanging flap. This method is...
    16 KB (2,112 words) - 01:32, 8 September 2024
  • Thumbnail for Okazaki fragments
    nucleotide is displaced into a flap and subsequently removed by FEN1. Dna2 endonuclease does not have a specific structure and their properties are not...
    33 KB (4,435 words) - 14:24, 7 June 2024
  • Thumbnail for Nuclease
    pair mismatches. For details see flap endonuclease. There are more than 900 restriction enzymes, some sequence specific and some not, have been isolated...
    22 KB (2,538 words) - 13:28, 11 September 2024
  • Thumbnail for DNA repair
    Research. 11 (2 Pt 1): 473–82. doi:10.1158/1078-0432.473.11.2. PMID 15701830. Wang K, Xie C, Chen D (May 2014). "Flap endonuclease 1 is a promising candidate...
    129 KB (15,900 words) - 22:25, 12 October 2024
  • Thumbnail for Proliferating cell nuclear antigen
    DNMT1 EP300 Establishment of Sister Chromatid Cohesion 2 Flap structure-specific endonuclease 1 GADD45A GADD45G HDAC1 HUS1 ING1 KCTD13 KIAA0101 Ku70 Ku80...
    53 KB (6,158 words) - 18:54, 23 April 2024
  • Thumbnail for APEX1
    APEX1 (redirect from APEX nuclease 1)
    same protein. APEX1 has been shown to interact with MUTYH, Flap structure-specific endonuclease 1 and XRCC1. Deficiency of APEX1 causes accummulation of DNA...
    11 KB (1,319 words) - 18:41, 13 August 2023
  • Thumbnail for Cyclin-dependent kinase 2
    CEBPA, Cyclin A1, Cyclin E1, Flap structure-specific endonuclease 1, ORC1L, P21, PPM1B, PPP2CA, Retinoblastoma-like protein 1, Retinoblastoma-like protein...
    35 KB (4,314 words) - 00:26, 6 July 2024