• Glucagon receptor agonists are a class of drugs under development for the treatment of obesity, non-alcoholic fatty liver disease, and congenital hyperinsulinism...
    6 KB (676 words) - 17:59, 5 December 2023
  • Glucagon-like peptide-1 (GLP-1) receptor agonists, also known as GLP-1 analogs, GLP-1DAs or incretin mimetics, are a class of anorectic drugs that reduce...
    37 KB (3,890 words) - 03:08, 12 August 2024
  • Thumbnail for Glucagon
    affect glucagon production. Excising the eyestalk in young crayfish produces glucagon-induced hyperglycemia. Glucagon binds to the glucagon receptor, a G...
    24 KB (2,821 words) - 06:18, 10 July 2024
  • Thumbnail for Glucagon-like peptide-1 receptor
    The glucagon-like peptide-1 receptor (GLP1R) is a G protein-coupled receptor (GPCR) found on beta cells of the pancreas and on neurons of the brain. It...
    33 KB (4,071 words) - 15:36, 30 July 2024
  • poly-agonist peptides are a class of drugs that activate multiple peptide hormone receptors including the glucagon-like peptide-1 (GLP-1) receptor. These...
    8 KB (899 words) - 10:09, 6 August 2024
  • Thumbnail for Retatrutide
    Retatrutide (category Glucagon receptor agonists)
    company Eli Lilly and Company. It is a triple glucagon hormone receptor agonist (GLP-1, GIP, and GCGR receptors). It has been shown to achieve a more than...
    4 KB (328 words) - 05:24, 6 August 2024
  • Thumbnail for Glucagon-like peptide-1
    GLP-1 is preserved in patients with type 2 diabetes. Glucagon-like peptide-1 receptor agonists gained approval as drugs to treat diabetes and obesity...
    26 KB (3,386 words) - 20:19, 8 August 2024
  • Mazdutide (category Glucagon receptor agonists)
    Mazdutide (also known as IBI362 or LY3305677) is a dual agonist of the GLP-1 receptor and glucagon receptor. It is an analog of oxyntomodulin (OXM). The drug...
    9 KB (284 words) - 09:11, 17 June 2024
  • Thumbnail for Alpha-2 adrenergic receptor
    as a moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist). Clonidine (also I1 agonist) Detomidine Dexmedetomidine Fadolmidine...
    25 KB (2,231 words) - 08:33, 22 August 2024
  • Survodutide (category Glucagon receptor agonists)
    peptide that works as a dual glucagon/GLP-1 receptor agonist. Unlike other dual GLP-1/glucagon dual agonists, it is a glucagon analog rather than an analog...
    7 KB (207 words) - 18:46, 16 June 2024