Hereditary spastic paraplegia (HSP) is a group of inherited diseases whose main feature is a progressive gait disorder. The disease presents with progressive...
36 KB (3,347 words) - 19:00, 17 April 2024
depending on whether additional clinical features are present besides spastic paraplegia, such as optic atrophy, ataxia, peripheral neuropathy, extrapyramidal...
31 KB (3,717 words) - 10:04, 5 April 2024
Spastic paraplegia 31 is a rare type of hereditary spastic paraplegia which is characterized by sensation anomalies of the lower extremities. People with...
7 KB (647 words) - 15:02, 1 February 2023
Spastic paraplegia 6 is a rare type of hereditary spastic paraplegia characterized by muscle tone and bladder anomalies associated with pes cavus and specific...
6 KB (493 words) - 06:01, 11 March 2023
SPG15 (disease) (redirect from Spastic paraplegia 15)
Spastic paraplegia 15 (SPG15) is a form of hereditary spastic paraplegia that commonly becomes apparent during childhood or adolescence (e.g. between ages...
12 KB (1,302 words) - 21:02, 2 December 2023
types of symptoms. Damage to the upper motor neuron typically causes spasticity including stiffness and increased tendon reflexes, and/or clonus, while...
130 KB (14,040 words) - 22:10, 27 August 2024
PLA2G6 (section Hereditary spastic paraplegia)
basal ganglia on magnetic resonance imaging. Hereditary spastic paraplegias are a diverse class of hereditary degenerative spinal cord disorders characterized...
16 KB (1,791 words) - 05:28, 7 July 2024
Warburg Micro syndrome (WARBM), a Complex Hereditary Spastic Paraplegia or RAB18 Deficiency, is a rare autosomal recessive genetic disorder characterized...
5 KB (306 words) - 20:29, 29 December 2023
is not routinely recommended because there are only rare instances of hereditary DLB. Many neurodegenerative conditions share cognitive and motor symptoms...
136 KB (14,528 words) - 18:35, 30 July 2024
dominant spastic paraplegia 10. KIF5A has been shown to interact with KLC1. Mutations in KIF5A have been reported to cause hereditary spastic paraplegia type...
9 KB (990 words) - 10:22, 29 December 2023